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Cheap flights from Knoxville (TYS) to Buffalo (BUF)

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0 Children (2~11)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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Cheap flights from Knoxville to Buffalo in January , February 2026

28 Jan - 04 Feb $ 417.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
28 Jan - 04 Feb $ 417.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
28 Jan - 04 Feb $ 417.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates

Last minute flights from Knoxville to Buffalo

28 Jan - 01 Feb $ 369.00
TYS
Knoxville
Allegiant Air
2 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
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24 Jan - 01 Feb $ 440.00
TYS
Knoxville
Allegiant Air
2 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
Pick dates
16 Jan - 01 Feb $ 531.00
TYS
Knoxville
Allegiant Air
1 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
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One-way flights to Buffalo from Knoxville

9:30 AM - 12:40 PM
United Airlines
1 Stops
4h 44m
TYS - BUF
$ 244
Kiwi
Pick dates
9:30 AM - 12:40 PM
United Airlines
1 Stops
4h 44m
TYS - BUF
$ 329
Kiwi
Pick dates
9:30 AM - 12:40 PM
United Airlines
1 Stops
4h 44m
TYS - BUF
$ 355
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.