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Cheap flights from Knoxville (TYS) to Buffalo (BUF)

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0 Children (2~11)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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Cheap flights from Knoxville to Buffalo in April , May 2026

30 Apr - 07 May $ 677.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
30 Apr - 07 May $ 677.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
30 Apr - 07 May $ 677.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to Buffalo

29 Apr - 01 May $ 739.00
TYS
Knoxville
Allegiant Air
2 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
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27 Apr - 01 May $ 941.00
TYS
Knoxville
Allegiant Air
3 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
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27 Apr - 01 May $ 1,003.00
TYS
Knoxville
Allegiant Air
3 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
2 STOPS
TYS
Knoxville
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One-way flights to Buffalo from Knoxville

9:40 AM - 12:52 PM
United Airlines
1 Stops
4h 37m
TYS - BUF
$ 344
Kiwi
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2:25 PM - 5:10 PM
United Airlines
1 Stops
4h 10m
TYS - BUF
$ 345
Kiwi
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9:50 AM - 12:45 PM
United Airlines
1 Stops
4h 20m
TYS - BUF
$ 345
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.