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Cheap flights from Knoxville (TYS) to Buffalo (BUF)

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0 Children (2~11)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
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Cheap flights from Knoxville to Buffalo in November , December 2025

27 Nov - 04 Dec $ 480.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
27 Nov - 04 Dec $ 480.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
27 Nov - 04 Dec $ 519.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to Buffalo

28 Nov - 01 Dec $ 513.00
TYS
Knoxville
Allegiant Air
1 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
1 STOPS
TYS
Knoxville
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24 Nov - 01 Dec $ 528.00
TYS
Knoxville
Allegiant Air
1 STOPS
BUF
Buffalo
BUF
Buffalo
Allegiant Air
1 STOPS
TYS
Knoxville
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27 Nov - 01 Dec $ 829.00
TYS
Knoxville
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
2 STOPS
TYS
Knoxville
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One-way flights to Buffalo from Knoxville

5:45 AM - 8:25 AM
United Airlines
1 Stops
4h 4m
TYS - BUF
$ 314
Kiwi
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2:25 PM - 5:15 PM
United Airlines
1 Stops
4h 21m
TYS - BUF
$ 316
Kiwi
Pick dates
5:45 AM - 8:25 AM
United Airlines
1 Stops
4h 3m
TYS - BUF
$ 346
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.