Earn point on your loyalty program!arrow arc left

Cheap flights from Myrtle Beach (MYR) to Buffalo (BUF)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)

How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Myrtle Beach to Buffalo in March , April 2026

31 Mar - 14 Apr $ 202.00
MYR
Myrtle Beach
Spirit Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Spirit Airlines
1 STOPS
MYR
Myrtle Beach
Pick dates
29 Mar - 14 Apr $ 324.00
MYR
Myrtle Beach
Spirit Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Spirit Airlines
1 STOPS
MYR
Myrtle Beach
Pick dates
15 Mar - 14 Apr $ 352.00
MYR
Myrtle Beach
Spirit Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Spirit Airlines
1 STOPS
MYR
Myrtle Beach
Pick dates

Last minute flights from Myrtle Beach to Buffalo

27 Mar - 01 Apr $ 954.00
MYR
Myrtle Beach
BREEZE
2 STOPS
BUF
Buffalo
BUF
Buffalo
BREEZE
3 STOPS
MYR
Myrtle Beach
Pick dates
29 Mar - 01 Apr $ 1,035.00
MYR
Myrtle Beach
BREEZE
1 STOPS
BUF
Buffalo
BUF
Buffalo
BREEZE
3 STOPS
MYR
Myrtle Beach
Pick dates
15 Mar - 01 Apr $ 1,064.00
MYR
Myrtle Beach
BREEZE
1 STOPS
BUF
Buffalo
BUF
Buffalo
BREEZE
3 STOPS
MYR
Myrtle Beach
Pick dates

One-way flights to Buffalo from Myrtle Beach

3:15 PM - 6:02 PM
United Airlines
1 Stops
5h 28m
MYR - BUF
$ 184
Kiwi
Pick dates
6:05 PM - 10:20 PM
United Airlines
1 Stops
5h 51m
MYR - BUF
$ 289
Kiwi
Pick dates
1:00 PM - 4:15 PM
United Airlines
1 Stops
4h 50m
MYR - BUF
$ 378
Kiwi
Pick dates

How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Myrtle Beach (MYR) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.