Earn point on your loyalty program!arrow arc left

Cheap flights from San Diego (SAN) to Buffalo (BUF)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from San Diego to Buffalo in April , May 2026

30 Apr - 05 May $ 292.00
SAN
San Diego
Frontier Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Frontier Airlines
2 STOPS
SAN
San Diego
Pick dates
16 Apr - 06 May $ 683.00
SAN
San Diego
Alaska Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates
16 Apr - 09 May $ 788.00
SAN
San Diego
Alaska Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates

Last minute flights from San Diego to Buffalo

27 Apr - 30 Apr $ 371.00
SAN
San Diego
Frontier Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Frontier Airlines
2 STOPS
SAN
San Diego
Pick dates
16 Apr - 30 Apr $ 896.00
SAN
San Diego
Alaska Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates
10 Apr - 30 Apr $ 962.00
SAN
San Diego
Alaska Airlines
2 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates

One-way flights to Buffalo from San Diego

7:24 PM - 9:10 AM
Frontier Airlines
2 Stops
12h 59m
SAN - BUF
$ 138
Kiwi
Pick dates
12:42 PM - 10:15 PM
Alaska Airlines
1 Stops
7h 57m
SAN - BUF
$ 347
Kiwi
Pick dates
10:52 AM - 6:02 PM
United Airlines
1 Stops
6h 51m
SAN - BUF
$ 368
Kiwi
Pick dates

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.