Earn point on your loyalty program!arrow arc left

Cheap flights from San Diego (SAN) to Buffalo (BUF)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from San Diego to Buffalo in November , December 2026

26 Nov - 05 Dec $ 476.00
SAN
San Diego
JetBlue Airways
1 STOPS
BUF
Buffalo
BUF
Buffalo
JetBlue Airways
1 STOPS
SAN
San Diego
Pick dates
19 Nov - 05 Dec $ 530.00
SAN
San Diego
JetBlue Airways
1 STOPS
BUF
Buffalo
BUF
Buffalo
JetBlue Airways
1 STOPS
SAN
San Diego
Pick dates
14 Nov - 03 Dec $ 707.00
SAN
San Diego
Alaska Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates

Last minute flights from San Diego to Buffalo

24 Nov - 30 Nov $ 728.00
SAN
San Diego
Alaska Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates
19 Nov - 30 Nov $ 757.00
SAN
San Diego
JetBlue Airways
1 STOPS
BUF
Buffalo
BUF
Buffalo
JetBlue Airways
1 STOPS
SAN
San Diego
Pick dates
14 Nov - 30 Nov $ 1,950.00
SAN
San Diego
Alaska Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates

One-way flights to Buffalo from San Diego

11:39 AM - 8:55 PM
JetBlue Airways
1 Stops
9h 19m
SAN - BUF
$ 295
Kiwi
Pick dates
11:39 AM - 8:55 PM
JetBlue Airways
1 Stops
9h 19m
SAN - BUF
$ 344
Kiwi
Pick dates
9:40 PM - 6:59 AM
JetBlue Airways
1 Stops
7h 46m
SAN - BUF
$ 459
Kiwi
Pick dates

How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.