Earn point on your loyalty program!arrow arc left

Cheap flights from St Louis (STL) to Buffalo (BUF)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)

How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from St Louis to Buffalo in April , May 2025

26 Apr - 03 May $ 531.00
STL
St Louis
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
STL
St Louis
Pick dates
26 Apr - 03 May $ 531.00
STL
St Louis
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
STL
St Louis
Pick dates
26 Apr - 03 May $ 531.00
STL
St Louis
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
STL
St Louis
Pick dates

Last minute flights from St Louis to Buffalo

23 Apr - 30 Apr $ 541.00
STL
St Louis
United Airlines
1 STOPS
BUF
Buffalo
BUF
Buffalo
United Airlines
1 STOPS
STL
St Louis
Pick dates

One-way flights to Buffalo from St Louis

8:00 AM - 10:35 AM
United Airlines
1 Stops
4h 20m
STL - BUF
$ 272
Kiwi
Pick dates
3:40 PM - 6:25 PM
United Airlines
1 Stops
4h 31m
STL - BUF
$ 272
Kiwi
Pick dates
8:00 AM - 10:35 AM
United Airlines
1 Stops
4h 20m
STL - BUF
$ 315
Kiwi
Pick dates

How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Buffalo (BUF)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.