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Cheap flights from Des Moines (DSM) to Charleston (CHS)

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0 Children (2~11)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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Cheap flights from Des Moines to Charleston in November , December 2025

24 Nov - 01 Dec $ 460.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Nov - 01 Dec $ 486.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Nov - 01 Dec $ 486.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to Charleston

26 Nov - 01 Dec $ 541.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
3 STOPS
DSM
Des Moines
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26 Nov - 01 Dec $ 542.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
2 STOPS
DSM
Des Moines
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26 Nov - 01 Dec $ 581.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates

One-way flights to Charleston from Des Moines

3:15 PM - 5:50 PM
United Airlines
1 Stops
4h 53m
DSM - CHS
$ 192
Kiwi
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8:02 AM - 4:00 PM
United Airlines
2 Stops
9h 9m
DSM - CHS
$ 197
Kiwi
Pick dates
8:02 AM - 10:40 AM
United Airlines
1 Stops
4h 53m
DSM - CHS
$ 227
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.