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Cheap flights from Des Moines (DSM) to Charleston (CHS)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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Cheap flights from Des Moines to Charleston in October , November 2026

25 Oct - 06 Nov $ 325.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
25 Oct - 13 Nov $ 332.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
29 Oct - 06 Nov $ 362.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to Charleston

25 Oct - 01 Nov $ 365.00
DSM
Des Moines
Allegiant Air
1 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
29 Oct - 01 Nov $ 402.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
30 Oct - 01 Nov $ 432.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
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One-way flights to Charleston from Des Moines

6:37 PM - 7:15 PM
BREEZE
1 Stops
25h 24m
DSM - CHS
$ 196
Kiwi
Pick dates
8:00 AM - 10:40 AM
United Airlines
1 Stops
4h 56m
DSM - CHS
$ 421
Kiwi
Pick dates
8:00 AM - 10:40 AM
United Airlines
1 Stops
4h 56m
DSM - CHS
$ 421
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.