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Cheap flights from Des Moines (DSM) to Charleston (CHS)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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Cheap flights from Des Moines to Charleston in February , March 2026

24 Feb - 03 Mar $ 462.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Feb - 03 Mar $ 462.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Feb - 03 Mar $ 462.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

Last minute flights from Des Moines to Charleston

21 Feb - 28 Feb $ 563.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
26 Feb - 28 Feb $ 565.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
21 Feb - 28 Feb $ 663.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

One-way flights to Charleston from Des Moines

8:00 AM - 10:35 AM
United Airlines
1 Stops
4h 52m
DSM - CHS
$ 269
Kiwi
Pick dates
8:00 AM - 10:35 AM
United Airlines
1 Stops
4h 52m
DSM - CHS
$ 309
Kiwi
Pick dates
3:24 PM - 6:15 PM
United Airlines
1 Stops
5h 3m
DSM - CHS
$ 309
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.