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Cheap flights from Des Moines (DSM) to Charleston (CHS)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
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Cheap flights from Des Moines to Charleston in September , October 2026

28 Sep - 30 Oct $ 621.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
28 Sep - 23 Oct $ 689.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
30 Sep - 07 Oct $ 912.00
DSM
Des Moines
United Airlines
1 STOPS
CHS
Charleston
CHS
Charleston
United Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to Charleston

28 Sep - 01 Oct $ 822.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
28 Sep - 01 Oct $ 828.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
28 Sep - 01 Oct $ 899.00
DSM
Des Moines
Allegiant Air
2 STOPS
CHS
Charleston
CHS
Charleston
Allegiant Air
2 STOPS
DSM
Des Moines
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One-way flights to Charleston from Des Moines

8:00 AM - 10:39 AM
United Airlines
1 Stops
5h 4m
DSM - CHS
$ 509
Kiwi
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3:11 PM - 6:10 PM
United Airlines
1 Stops
5h 22m
DSM - CHS
$ 509
Kiwi
Pick dates
11:27 AM - 2:25 PM
United Airlines
1 Stops
5h 35m
DSM - CHS
$ 509
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Charleston (CHS)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.