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Cheap flights from Des Moines (DSM) to Chicago (CHI)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)

How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)
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How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)
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How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)
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Cheap flights from Des Moines to Chicago in December 2025 , January 2026

31 Dec - 14 Jan $ 264.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates
16 Dec - 17 Jan $ 349.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates
16 Dec - 16 Jan $ 349.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates

Last minute flights from Des Moines to Chicago

27 Dec - 31 Dec $ 326.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates
27 Dec - 31 Dec $ 326.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates
25 Dec - 31 Dec $ 326.00
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
Pick dates

One-way flights to Chicago from Des Moines

3:14 PM - 3:14 PM
United Airlines
0 Stops
1h 39m
DSM - CHI
$ 140
Kiwi
Pick dates
11:15 AM - 11:15 AM
United Airlines
0 Stops
1h 35m
DSM - CHI
$ 179
Kiwi
Pick dates
3:17 PM - 3:17 PM
United Airlines
0 Stops
1h 31m
DSM - CHI
$ 225
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.