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Cheap flights from Knoxville (TYS) to Chicago (CHI)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)

How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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Cheap flights from Knoxville to Chicago in December 2025 , January 2026

31 Dec - 14 Jan $ 276.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates
16 Dec - 11 Jan $ 309.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates
16 Dec - 11 Jan $ 309.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates

Last minute flights from Knoxville to Chicago

24 Dec - 31 Dec $ 379.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates
24 Dec - 31 Dec $ 379.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates
17 Dec - 31 Dec $ 468.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates

One-way flights to Chicago from Knoxville

6:45 AM - 6:45 AM
United Airlines
0 Stops
2h 7m
TYS - CHI
$ 220
Kiwi
Pick dates
5:35 PM - 5:35 PM
United Airlines
0 Stops
1h 58m
TYS - CHI
$ 236
Kiwi
Pick dates
11:00 AM - 11:00 AM
United Airlines
0 Stops
1h 58m
TYS - CHI
$ 241
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.