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Cheap flights from Knoxville (TYS) to Chicago (CHI)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)

How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
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Cheap flights from Knoxville to Chicago in September , October 2026

30 Sep - 26 Oct $ 341.00
TYS
Knoxville
Allegiant Air
1 STOPS
CHI
Chicago
CHI
Chicago
Allegiant Air
DIRECT
TYS
Knoxville
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27 Sep - 11 Oct $ 667.00
TYS
Knoxville
United Airlines
1 STOPS
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
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27 Sep - 11 Oct $ 985.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates

Last minute flights from Knoxville to Chicago

28 Sep - 30 Sep $ 954.00
TYS
Knoxville
United Airlines
1 STOPS
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates
28 Sep - 30 Sep $ 964.00
TYS
Knoxville
United Airlines
1 STOPS
CHI
Chicago
CHI
Chicago
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
28 Sep - 30 Sep $ 1,229.00
TYS
Knoxville
United Airlines
DIRECT
CHI
Chicago
CHI
Chicago
United Airlines
DIRECT
TYS
Knoxville
Pick dates

One-way flights to Chicago from Knoxville

10:28 AM - 8:51 PM
Frontier Airlines
1 Stops
13h 31m
TYS - CHI
$ 264
Kiwi
Pick dates
6:00 AM - 6:00 AM
United Airlines
0 Stops
1h 56m
TYS - CHI
$ 458
Kiwi
Pick dates
10:42 AM - 10:42 AM
United Airlines
0 Stops
1h 58m
TYS - CHI
$ 458
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Chicago (CHI)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.