Earn point on your loyalty program!arrow arc left

Cheap flights from Charlotte (CLT) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Charlotte to Des Moines in February , March 2026

19 Feb - 24 Mar $ 231.00
CLT
Charlotte
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
CLT
Charlotte
Pick dates
26 Feb - 24 Mar $ 239.00
CLT
Charlotte
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
CLT
Charlotte
Pick dates
26 Feb - 24 Mar $ 250.00
CLT
Charlotte
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
CLT
Charlotte
Pick dates

Last minute flights from Charlotte to Des Moines

21 Feb - 28 Feb $ 495.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates
21 Feb - 28 Feb $ 495.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates
21 Feb - 28 Feb $ 495.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates

One-way flights to Des Moines from Charlotte

1:24 PM - 8:32 PM
Allegiant Air
1 Stops
10h 42m
CLT - DSM
$ 144
Kiwi
Pick dates
10:42 AM - 4:20 PM
United Airlines
1 Stops
8h 5m
CLT - DSM
$ 377
Kiwi
Pick dates
10:42 AM - 1:00 PM
United Airlines
1 Stops
4h 45m
CLT - DSM
$ 431
Kiwi
Pick dates

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.