Earn point on your loyalty program!arrow arc left

Cheap flights from Charlotte (CLT) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Charlotte to Des Moines in November , December 2026

24 Nov - 13 Dec $ 278.00
CLT
Charlotte
JetBlue Airways
1 STOPS
DSM
Des Moines
DSM
Des Moines
JetBlue Airways
1 STOPS
CLT
Charlotte
Pick dates
19 Nov - 13 Dec $ 311.00
CLT
Charlotte
JetBlue Airways
1 STOPS
DSM
Des Moines
DSM
Des Moines
JetBlue Airways
1 STOPS
CLT
Charlotte
Pick dates
19 Nov - 10 Dec $ 383.00
CLT
Charlotte
JetBlue Airways
1 STOPS
DSM
Des Moines
DSM
Des Moines
JetBlue Airways
1 STOPS
CLT
Charlotte
Pick dates

Last minute flights from Charlotte to Des Moines

24 Nov - 01 Dec $ 333.00
CLT
Charlotte
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CLT
Charlotte
Pick dates
19 Nov - 01 Dec $ 367.00
CLT
Charlotte
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CLT
Charlotte
Pick dates
22 Nov - 01 Dec $ 426.00
CLT
Charlotte
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CLT
Charlotte
Pick dates

One-way flights to Des Moines from Charlotte

8:54 AM - 7:20 PM
Allegiant Air
1 Stops
13h 59m
CLT - DSM
$ 149
Kiwi
Pick dates
9:00 AM - 1:38 PM
Allegiant Air
1 Stops
8h 11m
CLT - DSM
$ 183
Kiwi
Pick dates
8:54 AM - 1:38 PM
Allegiant Air
1 Stops
8h 17m
CLT - DSM
$ 243
Kiwi
Pick dates

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.