Earn point on your loyalty program!arrow arc left

Cheap flights from Charlotte (CLT) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Charlotte to Des Moines in August , September 2026

29 Aug - 05 Sep $ 555.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates
26 Aug - 02 Sep $ 555.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates
29 Aug - 05 Sep $ 555.00
CLT
Charlotte
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLT
Charlotte
Pick dates

Last minute flights from Charlotte to Des Moines

29 Aug - 01 Sep $ 366.00
CLT
Charlotte
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLT
Charlotte
Pick dates
26 Aug - 01 Sep $ 373.00
CLT
Charlotte
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLT
Charlotte
Pick dates
17 Aug - 01 Sep $ 454.00
CLT
Charlotte
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLT
Charlotte
Pick dates

One-way flights to Des Moines from Charlotte

12:01 PM - 9:33 PM
Allegiant Air
2 Stops
12h 13m
CLT - DSM
$ 293
Kiwi
Pick dates
5:36 PM - 7:55 PM
United Airlines
1 Stops
4h 47m
CLT - DSM
$ 466
Kiwi
Pick dates
5:36 PM - 7:55 PM
United Airlines
1 Stops
4h 47m
CLT - DSM
$ 467
Kiwi
Pick dates

How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.