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Cheap flights from Chicago (CHI) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)

How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)
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How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)
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How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)
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Cheap flights from Chicago to Des Moines in September , October 2026

30 Sep - 01 Oct $ 379.00
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
Pick dates
30 Sep - 07 Oct $ 379.00
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
Pick dates
30 Sep - 07 Oct $ 379.00
CHI
Chicago
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
CHI
Chicago
Pick dates

Last minute flights from Chicago to Des Moines

27 Sep - 30 Sep $ 454.00
CHI
Chicago
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CHI
Chicago
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27 Sep - 30 Sep $ 468.00
CHI
Chicago
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CHI
Chicago
Pick dates
24 Sep - 30 Sep $ 499.00
CHI
Chicago
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CHI
Chicago
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One-way flights to Des Moines from Chicago

12:50 PM - 12:50 PM
United Airlines
0 Stops
1h 25m
CHI - DSM
$ 155
Kiwi
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12:54 PM - 12:54 PM
United Airlines
0 Stops
1h 26m
CHI - DSM
$ 284
Kiwi
Pick dates
12:54 PM - 12:54 PM
United Airlines
0 Stops
1h 26m
CHI - DSM
$ 284
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.