Earn point on your loyalty program!arrow arc left

Cheap flights from Cleveland (CLE) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Cleveland to Des Moines in February , March 2026

28 Feb - 06 Mar $ 755.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
28 Feb - 06 Mar $ 755.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
28 Feb - 06 Mar $ 755.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates

One-way flights to Des Moines from Cleveland

6:06 PM - 8:10 PM
United Airlines
1 Stops
4h 35m
CLE - DSM
$ 379
Kiwi
Pick dates
4:16 PM - 8:10 PM
United Airlines
1 Stops
6h 25m
CLE - DSM
$ 379
Kiwi
Pick dates
4:25 PM - 8:51 PM
United Airlines
1 Stops
8h 18m
CLE - DSM
$ 379
Kiwi
Pick dates

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.