Earn point on your loyalty program!arrow arc left

Cheap flights from Cleveland (CLE) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Cleveland to Des Moines in October , November 2026

30 Oct - 13 Nov $ 308.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates
30 Oct - 15 Nov $ 351.00
CLE
Cleveland
JetBlue Airways
1 STOPS
DSM
Des Moines
DSM
Des Moines
JetBlue Airways
1 STOPS
CLE
Cleveland
Pick dates
30 Oct - 19 Nov $ 390.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates

Last minute flights from Cleveland to Des Moines

30 Oct - 01 Nov $ 561.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
3 STOPS
CLE
Cleveland
Pick dates
30 Oct - 01 Nov $ 597.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
3 STOPS
CLE
Cleveland
Pick dates
29 Oct - 01 Nov $ 694.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
3 STOPS
CLE
Cleveland
Pick dates

One-way flights to Des Moines from Cleveland

1:34 PM - 7:53 PM
Allegiant Air
1 Stops
9h 34m
CLE - DSM
$ 154
Kiwi
Pick dates
9:00 AM - 11:10 AM
United Airlines
1 Stops
4h 42m
CLE - DSM
$ 333
Kiwi
Pick dates
4:09 PM - 5:45 PM
United Airlines
1 Stops
4h 7m
CLE - DSM
$ 339
Kiwi
Pick dates

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.