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Cheap flights from Cleveland (CLE) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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Cheap flights from Cleveland to Des Moines in December 2025 , January 2026

31 Dec - 07 Jan $ 362.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
31 Dec - 07 Jan $ 362.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
31 Dec - 07 Jan $ 362.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates

Last minute flights from Cleveland to Des Moines

24 Dec - 31 Dec $ 376.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
24 Dec - 31 Dec $ 376.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
24 Dec - 31 Dec $ 468.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
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One-way flights to Des Moines from Cleveland

10:55 AM - 12:59 PM
United Airlines
1 Stops
4h 38m
CLE - DSM
$ 172
Kiwi
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5:53 PM - 8:10 PM
United Airlines
1 Stops
4h 47m
CLE - DSM
$ 172
Kiwi
Pick dates
2:14 PM - 4:31 PM
United Airlines
1 Stops
4h 51m
CLE - DSM
$ 172
Kiwi
Pick dates

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.