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Cheap flights from Cleveland (CLE) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
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Cheap flights from Cleveland to Des Moines in April , May 2026

29 Apr - 06 May $ 399.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
29 Apr - 06 May $ 399.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
Pick dates
29 Apr - 06 May $ 404.00
CLE
Cleveland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CLE
Cleveland
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Last minute flights from Cleveland to Des Moines

15 Apr - 30 Apr $ 276.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLE
Cleveland
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23 Apr - 30 Apr $ 350.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates
26 Apr - 30 Apr $ 371.00
CLE
Cleveland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
CLE
Cleveland
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One-way flights to Des Moines from Cleveland

11:00 AM - 12:59 PM
United Airlines
1 Stops
4h 25m
CLE - DSM
$ 200
Kiwi
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11:00 AM - 12:59 PM
United Airlines
1 Stops
4h 25m
CLE - DSM
$ 309
Kiwi
Pick dates
8:00 PM - 9:40 PM
United Airlines
1 Stops
4h 17m
CLE - DSM
$ 398
Kiwi
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.