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Cheap flights from Columbus (CMH) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)

How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)
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How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)
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How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)
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Cheap flights from Columbus to Des Moines in December 2025 , January 2026

30 Dec - 06 Jan $ 422.00
CMH
Columbus
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CMH
Columbus
Pick dates
30 Dec - 06 Jan $ 422.00
CMH
Columbus
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CMH
Columbus
Pick dates
30 Dec - 06 Jan $ 422.00
CMH
Columbus
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
CMH
Columbus
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Last minute flights from Columbus to Des Moines

24 Dec - 31 Dec $ 656.00
CMH
Columbus
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
CMH
Columbus
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30 Dec - 31 Dec $ 739.00
CMH
Columbus
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
CMH
Columbus
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28 Dec - 31 Dec $ 771.00
CMH
Columbus
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
CMH
Columbus
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One-way flights to Des Moines from Columbus

5:45 PM - 8:10 PM
United Airlines
1 Stops
4h 55m
CMH - DSM
$ 147
Kiwi
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2:16 PM - 4:31 PM
United Airlines
1 Stops
4h 49m
CMH - DSM
$ 289
Kiwi
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4:15 PM - 6:05 PM
United Airlines
1 Stops
4h 14m
CMH - DSM
$ 379
Kiwi
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How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Columbus (CMH) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.