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Cheap flights from Detroit (DTW) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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Cheap flights from Detroit to Des Moines in December 2025 , January 2026

23 Dec - 26 Jan $ 363.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
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23 Dec - 12 Jan $ 372.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
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23 Dec - 23 Jan $ 385.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
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Last minute flights from Detroit to Des Moines

18 Dec - 31 Dec $ 651.00
DTW
Detroit
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
DTW
Detroit
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20 Dec - 31 Dec $ 654.00
DTW
Detroit
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
DTW
Detroit
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20 Dec - 31 Dec $ 654.00
DTW
Detroit
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
DTW
Detroit
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One-way flights to Des Moines from Detroit

2:43 PM - 8:44 PM
Allegiant Air
1 Stops
9h 27m
DTW - DSM
$ 235
Kiwi
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6:00 PM - 12:59 PM
United Airlines
1 Stops
21h 33m
DTW - DSM
$ 303
Kiwi
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11:20 AM - 12:59 PM
United Airlines
1 Stops
4h 13m
DTW - DSM
$ 548
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.