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Cheap flights from Detroit (DTW) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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Cheap flights from Detroit to Des Moines in April , May 2026

30 Apr - 11 May $ 413.00
DTW
Detroit
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
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30 Apr - 11 May $ 429.00
DTW
Detroit
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
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27 Apr - 11 May $ 467.00
DTW
Detroit
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
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Last minute flights from Detroit to Des Moines

27 Apr - 30 Apr $ 759.00
DTW
Detroit
Spirit Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
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27 Apr - 30 Apr $ 1,062.00
DTW
Detroit
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
DTW
Detroit
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27 Apr - 30 Apr $ 1,062.00
DTW
Detroit
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
DTW
Detroit
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One-way flights to Des Moines from Detroit

6:00 AM - 1:06 PM
Allegiant Air
2 Stops
13h 1m
DTW - DSM
$ 337
Kiwi
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4:10 PM - 5:50 PM
United Airlines
1 Stops
4h 16m
DTW - DSM
$ 507
Kiwi
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8:10 PM - 9:40 PM
United Airlines
1 Stops
4h 7m
DTW - DSM
$ 577
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.