Earn point on your loyalty program!arrow arc left

Cheap flights from Detroit (DTW) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Detroit to Des Moines in April , May 2026

16 Apr - 08 May $ 331.00
DTW
Detroit
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
Pick dates
16 Apr - 11 May $ 331.00
DTW
Detroit
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
Pick dates
16 Apr - 15 May $ 342.00
DTW
Detroit
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
DTW
Detroit
Pick dates

Last minute flights from Detroit to Des Moines

09 Apr - 30 Apr $ 336.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates
26 Apr - 30 Apr $ 345.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates
16 Apr - 30 Apr $ 370.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates

One-way flights to Des Moines from Detroit

6:10 AM - 1:25 PM
Allegiant Air
1 Stops
10h 50m
DTW - DSM
$ 185
Kiwi
Pick dates
8:10 PM - 9:40 PM
United Airlines
1 Stops
4h 7m
DTW - DSM
$ 539
Kiwi
Pick dates
8:10 PM - 9:40 PM
United Airlines
1 Stops
4h 7m
DTW - DSM
$ 540
Kiwi
Pick dates

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.