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Cheap flights from Detroit (DTW) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
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Cheap flights from Detroit to Des Moines in March , April 2026

18 Mar - 16 Apr $ 372.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates
18 Mar - 23 Apr $ 383.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates
18 Mar - 26 Apr $ 387.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
DTW
Detroit
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Last minute flights from Detroit to Des Moines

18 Mar - 01 Apr $ 827.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
DTW
Detroit
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09 Mar - 01 Apr $ 850.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
DTW
Detroit
Pick dates
25 Mar - 01 Apr $ 850.00
DTW
Detroit
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
DTW
Detroit
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One-way flights to Des Moines from Detroit

11:54 AM - 4:30 PM
Frontier Airlines
1 Stops
8h 22m
DTW - DSM
$ 209
Kiwi
Pick dates
9:00 AM - 5:40 PM
United Airlines
1 Stops
12h 27m
DTW - DSM
$ 432
Kiwi
Pick dates
10:28 AM - 11:50 AM
United Airlines
1 Stops
3h 55m
DTW - DSM
$ 499
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.