Earn point on your loyalty program!arrow arc left

Cheap flights from Houston (HOU) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Houston to Des Moines in November , December 2025

28 Nov - 13 Dec $ 347.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates
28 Nov - 13 Dec $ 347.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates
28 Nov - 09 Dec $ 353.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates

Last minute flights from Houston to Des Moines

27 Nov - 30 Nov $ 384.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
HOU
Houston
Pick dates
27 Nov - 30 Nov $ 394.00
HOU
Houston
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
HOU
Houston
Pick dates
26 Nov - 30 Nov $ 709.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates

One-way flights to Des Moines from Houston

11:48 AM - 4:18 PM
Frontier Airlines
1 Stops
7h 13m
HOU - DSM
$ 206
Kiwi
Pick dates
7:20 AM - 9:45 AM
United Airlines
1 Stops
5h 11m
HOU - DSM
$ 319
Kiwi
Pick dates
11:55 AM - 11:55 AM
United Airlines
0 Stops
2h 16m
HOU - DSM
$ 414
Kiwi
Pick dates

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.