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Cheap flights from Houston (HOU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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Cheap flights from Houston to Des Moines in March , April 2026

25 Mar - 03 Apr $ 354.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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25 Mar - 03 Apr $ 354.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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25 Mar - 03 Apr $ 380.00
HOU
Houston
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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Last minute flights from Houston to Des Moines

25 Mar - 01 Apr $ 791.00
HOU
Houston
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
HOU
Houston
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28 Mar - 01 Apr $ 820.00
HOU
Houston
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
HOU
Houston
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30 Mar - 01 Apr $ 858.00
HOU
Houston
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
HOU
Houston
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One-way flights to Des Moines from Houston

9:57 AM - 9:57 AM
United Airlines
0 Stops
6h 10m
HOU - DSM
$ 186
Kiwi
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12:01 PM - 12:01 PM
United Airlines
0 Stops
2h 17m
HOU - DSM
$ 494
Kiwi
Pick dates
12:01 PM - 12:01 PM
United Airlines
0 Stops
2h 17m
HOU - DSM
$ 494
Kiwi
Pick dates

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.