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Cheap flights from Houston (HOU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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Cheap flights from Houston to Des Moines in December 2025 , January 2026

30 Dec - 06 Jan $ 316.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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25 Dec - 12 Jan $ 334.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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25 Dec - 08 Jan $ 334.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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Last minute flights from Houston to Des Moines

24 Dec - 31 Dec $ 475.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
HOU
Houston
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24 Dec - 31 Dec $ 503.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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24 Dec - 31 Dec $ 953.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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One-way flights to Des Moines from Houston

7:20 AM - 4:31 PM
United Airlines
1 Stops
10h 45m
HOU - DSM
$ 285
Kiwi
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9:30 AM - 12:59 PM
United Airlines
1 Stops
5h 3m
HOU - DSM
$ 298
Kiwi
Pick dates
11:55 AM - 11:55 AM
United Airlines
0 Stops
2h 24m
HOU - DSM
$ 399
Kiwi
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.