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Cheap flights from Houston (HOU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
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Cheap flights from Houston to Des Moines in April , May 2026

25 Apr - 09 May $ 349.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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25 Apr - 09 May $ 349.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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23 Apr - 23 May $ 349.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates

Last minute flights from Houston to Des Moines

23 Apr - 30 Apr $ 349.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
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23 Apr - 30 Apr $ 359.00
HOU
Houston
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
DIRECT
HOU
Houston
Pick dates
23 Apr - 30 Apr $ 359.00
HOU
Houston
United Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
HOU
Houston
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One-way flights to Des Moines from Houston

6:45 AM - 10:25 AM
Frontier Airlines
1 Stops
6h 24m
HOU - DSM
$ 138
Kiwi
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7:20 AM - 10:52 AM
United Airlines
1 Stops
5h 9m
HOU - DSM
$ 321
Kiwi
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12:00 PM - 12:00 PM
United Airlines
0 Stops
2h 22m
HOU - DSM
$ 524
Kiwi
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How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.