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Cheap flights from Mcallen (MFE) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)

How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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Cheap flights from Mcallen to Des Moines in November , December 2025

27 Nov - 02 Dec $ 480.00
MFE
Mcallen
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
MFE
Mcallen
Pick dates
27 Nov - 02 Dec $ 485.00
MFE
Mcallen
United Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
MFE
Mcallen
Pick dates
27 Nov - 02 Dec $ 485.00
MFE
Mcallen
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
2 STOPS
MFE
Mcallen
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Last minute flights from Mcallen to Des Moines

27 Nov - 01 Dec $ 585.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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25 Nov - 01 Dec $ 646.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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24 Nov - 01 Dec $ 749.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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One-way flights to Des Moines from Mcallen

7:00 AM - 12:05 PM
United Airlines
1 Stops
7h 21m
MFE - DSM
$ 259
Kiwi
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7:00 AM - 12:59 PM
United Airlines
2 Stops
7h 19m
MFE - DSM
$ 264
Kiwi
Pick dates
9:50 AM - 11:55 AM
United Airlines
1 Stops
4h 21m
MFE - DSM
$ 315
Kiwi
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.