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Cheap flights from Mcallen (MFE) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)

How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
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Cheap flights from Mcallen to Des Moines in January , February 2026

28 Jan - 04 Feb $ 374.00
MFE
Mcallen
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
MFE
Mcallen
Pick dates
27 Jan - 03 Feb $ 374.00
MFE
Mcallen
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
MFE
Mcallen
Pick dates
27 Jan - 03 Feb $ 374.00
MFE
Mcallen
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
MFE
Mcallen
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Last minute flights from Mcallen to Des Moines

28 Jan - 01 Feb $ 424.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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29 Jan - 01 Feb $ 459.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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22 Jan - 01 Feb $ 487.00
MFE
Mcallen
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
MFE
Mcallen
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One-way flights to Des Moines from Mcallen

9:30 AM - 12:00 PM
United Airlines
1 Stops
4h 52m
MFE - DSM
$ 278
Kiwi
Pick dates
12:04 PM - 10:39 AM
Allegiant Air
1 Stops
27h 36m
MFE - DSM
$ 303
Kiwi
Pick dates
9:30 AM - 12:00 PM
United Airlines
1 Stops
4h 52m
MFE - DSM
$ 316
Kiwi
Pick dates

How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.