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Cheap flights from Portland (PDX) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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Cheap flights from Portland to Des Moines in October , November 2026

29 Oct - 24 Nov $ 574.00
PDX
Portland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
PDX
Portland
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26 Oct - 10 Nov $ 812.00
PDX
Portland
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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26 Oct - 04 Nov $ 834.00
PDX
Portland
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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Last minute flights from Portland to Des Moines

27 Oct - 31 Oct $ 834.00
PDX
Portland
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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27 Oct - 31 Oct $ 864.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
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27 Oct - 31 Oct $ 988.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
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One-way flights to Des Moines from Portland

12:31 PM - 5:58 PM
Allegiant Air
1 Stops
8h 19m
PDX - DSM
$ 376
Kiwi
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7:00 AM - 3:59 PM
United Airlines
1 Stops
8h 27m
PDX - DSM
$ 483
Kiwi
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9:00 AM - 1:25 PM
United Airlines
1 Stops
5h 7m
PDX - DSM
$ 493
Kiwi
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.