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Cheap flights from Portland (PDX) to Des Moines (DSM)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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Cheap flights from Portland to Des Moines in November , December 2025

30 Nov - 21 Dec $ 399.00
PDX
Portland
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
PDX
Portland
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28 Nov - 10 Dec $ 755.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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30 Nov - 10 Dec $ 845.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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Last minute flights from Portland to Des Moines

29 Nov - 01 Dec $ 690.00
PDX
Portland
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
PDX
Portland
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28 Nov - 30 Nov $ 1,766.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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24 Nov - 30 Nov $ 1,866.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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One-way flights to Des Moines from Portland

7:09 PM - 6:35 AM
Allegiant Air
1 Stops
14h 17m
PDX - DSM
$ 268
Kiwi
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4:02 PM - 8:51 PM
United Airlines
1 Stops
5h 42m
PDX - DSM
$ 419
Kiwi
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5:00 AM - 9:45 AM
United Airlines
1 Stops
5h 31m
PDX - DSM
$ 480
Kiwi
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.