Earn point on your loyalty program!arrow arc left

Cheap flights from Portland (PDX) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Portland to Des Moines in July , August 2026

30 Jul - 18 Aug $ 300.00
PDX
Portland
Allegiant Air
DIRECT
DSM
Des Moines
DSM
Des Moines
Allegiant Air
DIRECT
PDX
Portland
Pick dates
30 Jul - 09 Aug $ 440.00
PDX
Portland
Allegiant Air
DIRECT
DSM
Des Moines
DSM
Des Moines
Allegiant Air
DIRECT
PDX
Portland
Pick dates
30 Jul - 04 Aug $ 522.00
PDX
Portland
Allegiant Air
DIRECT
DSM
Des Moines
DSM
Des Moines
Allegiant Air
DIRECT
PDX
Portland
Pick dates

Last minute flights from Portland to Des Moines

30 Jul - 01 Aug $ 526.00
PDX
Portland
Frontier Airlines
DIRECT
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
PDX
Portland
Pick dates
29 Jul - 31 Jul $ 1,097.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates
29 Jul - 31 Jul $ 1,097.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates

One-way flights to Des Moines from Portland

5:35 PM - 5:35 PM
Allegiant Air
0 Stops
3h 21m
PDX - DSM
$ 228
Kiwi
Pick dates
11:29 AM - 11:29 AM
Allegiant Air
0 Stops
3h 21m
PDX - DSM
$ 322
Kiwi
Pick dates
8:50 AM - 1:30 PM
United Airlines
1 Stops
5h 21m
PDX - DSM
$ 549
Kiwi
Pick dates

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.