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Cheap flights from Portland (PDX) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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Cheap flights from Portland to Des Moines in February , March 2026

28 Feb - 04 Mar $ 477.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
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13 Feb - 07 Mar $ 672.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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06 Feb - 04 Mar $ 772.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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Last minute flights from Portland to Des Moines

23 Feb - 28 Feb $ 582.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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14 Feb - 28 Feb $ 677.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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06 Feb - 28 Feb $ 772.00
PDX
Portland
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
PDX
Portland
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One-way flights to Des Moines from Portland

12:57 PM - 7:55 PM
United Airlines
1 Stops
7h 23m
PDX - DSM
$ 274
Kiwi
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11:09 AM - 10:39 AM
Allegiant Air
1 Stops
26h 31m
PDX - DSM
$ 362
Kiwi
Pick dates
1:24 PM - 5:45 PM
United Airlines
1 Stops
5h 10m
PDX - DSM
$ 517
Kiwi
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.