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Cheap flights from Portland (PDX) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
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Cheap flights from Portland to Des Moines in January , February 2026

31 Jan - 07 Feb $ 532.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates
27 Jan - 03 Feb $ 532.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates
27 Jan - 03 Feb $ 532.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
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Last minute flights from Portland to Des Moines

24 Jan - 31 Jan $ 732.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates
16 Jan - 31 Jan $ 836.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
Pick dates
16 Jan - 31 Jan $ 1,027.00
PDX
Portland
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PDX
Portland
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One-way flights to Des Moines from Portland

1:24 PM - 5:45 PM
United Airlines
1 Stops
5h 10m
PDX - DSM
$ 314
Kiwi
Pick dates
11:59 AM - 4:37 PM
Frontier Airlines
1 Stops
29h 24m
PDX - DSM
$ 388
Kiwi
Pick dates
1:24 PM - 5:45 PM
United Airlines
1 Stops
5h 10m
PDX - DSM
$ 419
Kiwi
Pick dates

How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Portland (PDX) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.