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Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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Cheap flights from Raleigh Durham to Des Moines in April , May 2026

28 Apr - 05 May $ 351.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
30 Apr - 07 May $ 387.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
30 Apr - 09 May $ 387.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
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Last minute flights from Raleigh Durham to Des Moines

22 Apr - 01 May $ 312.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates
15 Apr - 01 May $ 332.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates
09 Apr - 01 May $ 431.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
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One-way flights to Des Moines from Raleigh Durham

6:20 AM - 9:01 AM
United Airlines
1 Stops
5h 17m
RDU - DSM
$ 197
Kiwi
Pick dates
5:25 PM - 8:00 PM
United Airlines
1 Stops
5h 7m
RDU - DSM
$ 379
Kiwi
Pick dates
5:25 PM - 8:00 PM
United Airlines
1 Stops
5h 7m
RDU - DSM
$ 382
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.