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Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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Cheap flights from Raleigh Durham to Des Moines in December 2025 , January 2026

25 Dec - 01 Jan $ 394.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
30 Dec - 06 Jan $ 439.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
29 Dec - 07 Jan $ 439.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
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Last minute flights from Raleigh Durham to Des Moines

29 Dec - 31 Dec $ 487.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
22 Dec - 31 Dec $ 504.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
22 Dec - 31 Dec $ 590.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates

One-way flights to Des Moines from Raleigh Durham

6:31 AM - 9:02 AM
United Airlines
1 Stops
5h 19m
RDU - DSM
$ 169
Kiwi
Pick dates
8:29 AM - 12:59 PM
United Airlines
1 Stops
7h 4m
RDU - DSM
$ 170
Kiwi
Pick dates
5:26 PM - 8:10 PM
United Airlines
1 Stops
5h 11m
RDU - DSM
$ 504
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.