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Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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Cheap flights from Raleigh Durham to Des Moines in May , June 2026

28 May - 29 Jun $ 373.00
RDU
Raleigh Durham
BREEZE
1 STOPS
DSM
Des Moines
DSM
Des Moines
BREEZE
2 STOPS
RDU
Raleigh Durham
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28 May - 15 Jun $ 392.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
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31 May - 15 Jun $ 398.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
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Last minute flights from Raleigh Durham to Des Moines

28 May - 01 Jun $ 608.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
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22 May - 31 May $ 1,128.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
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22 May - 31 May $ 1,128.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
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One-way flights to Des Moines from Raleigh Durham

5:12 PM - 8:13 PM
United Airlines
1 Stops
5h 33m
RDU - DSM
$ 221
Kiwi
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11:35 AM - 4:42 PM
United Airlines
1 Stops
7h 39m
RDU - DSM
$ 221
Kiwi
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6:15 AM - 8:52 AM
United Airlines
1 Stops
5h 12m
RDU - DSM
$ 488
Kiwi
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.