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Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
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Cheap flights from Raleigh Durham to Des Moines in March , April 2026

16 Mar - 26 Apr $ 320.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
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25 Mar - 26 Apr $ 329.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
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25 Mar - 26 Apr $ 343.00
RDU
Raleigh Durham
Spirit Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
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Last minute flights from Raleigh Durham to Des Moines

16 Mar - 01 Apr $ 796.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
RDU
Raleigh Durham
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25 Mar - 01 Apr $ 805.00
RDU
Raleigh Durham
Spirit Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
RDU
Raleigh Durham
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18 Mar - 01 Apr $ 838.00
RDU
Raleigh Durham
Spirit Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
3 STOPS
RDU
Raleigh Durham
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One-way flights to Des Moines from Raleigh Durham

5:20 PM - 7:55 PM
United Airlines
1 Stops
5h 7m
RDU - DSM
$ 179
Kiwi
Pick dates
10:22 AM - 12:57 PM
United Airlines
1 Stops
5h 2m
RDU - DSM
$ 346
Kiwi
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6:30 AM - 8:50 AM
United Airlines
1 Stops
4h 58m
RDU - DSM
$ 347
Kiwi
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.