Earn point on your loyalty program!arrow arc left

Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Raleigh Durham to Des Moines in January , February 2026

29 Jan - 14 Feb $ 234.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
29 Jan - 20 Feb $ 262.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
29 Jan - 20 Feb $ 302.00
RDU
Raleigh Durham
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates

Last minute flights from Raleigh Durham to Des Moines

29 Jan - 31 Jan $ 532.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
29 Jan - 31 Jan $ 532.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
27 Jan - 31 Jan $ 537.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates

One-way flights to Des Moines from Raleigh Durham

3:08 PM - 8:06 PM
Allegiant Air
1 Stops
8h 38m
RDU - DSM
$ 142
Kiwi
Pick dates
10:00 AM - 1:09 PM
United Airlines
1 Stops
5h 33m
RDU - DSM
$ 346
Kiwi
Pick dates
1:29 PM - 4:15 PM
United Airlines
1 Stops
5h 18m
RDU - DSM
$ 349
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.