Earn point on your loyalty program!arrow arc left

Cheap flights from Raleigh Durham (RDU) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Raleigh Durham to Des Moines in November , December 2025

26 Nov - 08 Dec $ 370.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
26 Nov - 15 Dec $ 380.00
RDU
Raleigh Durham
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
26 Nov - 01 Dec $ 430.00
RDU
Raleigh Durham
BREEZE
1 STOPS
DSM
Des Moines
DSM
Des Moines
BREEZE
1 STOPS
RDU
Raleigh Durham
Pick dates

Last minute flights from Raleigh Durham to Des Moines

27 Nov - 01 Dec $ 577.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
27 Nov - 01 Dec $ 577.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
23 Nov - 01 Dec $ 870.00
RDU
Raleigh Durham
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates

One-way flights to Des Moines from Raleigh Durham

2:14 PM - 6:50 PM
Allegiant Air
1 Stops
7h 55m
RDU - DSM
$ 250
Kiwi
Pick dates
6:30 AM - 9:06 AM
United Airlines
1 Stops
5h 12m
RDU - DSM
$ 375
Kiwi
Pick dates
1:30 PM - 4:05 PM
United Airlines
1 Stops
4h 55m
RDU - DSM
$ 504
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.