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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in December 2025 , January 2026

24 Dec - 12 Jan $ 255.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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24 Dec - 26 Jan $ 260.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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22 Dec - 12 Jan $ 311.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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Last minute flights from Roanoke to Des Moines

24 Dec - 02 Jan $ 493.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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22 Dec - 02 Jan $ 549.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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23 Dec - 02 Jan $ 592.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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One-way flights to Des Moines from Roanoke

8:55 PM - 4:54 PM
Allegiant Air
1 Stops
23h 2m
ROA - DSM
$ 111
Kiwi
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10:52 AM - 12:59 PM
United Airlines
1 Stops
4h 41m
ROA - DSM
$ 392
Kiwi
Pick dates
10:52 AM - 12:59 PM
United Airlines
1 Stops
4h 41m
ROA - DSM
$ 427
Kiwi
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.