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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in August , September 2026

24 Aug - 28 Sep $ 580.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
28 Aug - 28 Sep $ 629.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
24 Aug - 21 Sep $ 655.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates

One-way flights to Des Moines from Roanoke

2:36 PM - 7:30 PM
Allegiant Air
1 Stops
7h 50m
ROA - DSM
$ 270
Kiwi
Pick dates
10:44 AM - 12:50 PM
United Airlines
1 Stops
4h 32m
ROA - DSM
$ 389
Kiwi
Pick dates
10:44 AM - 12:50 PM
United Airlines
1 Stops
4h 32m
ROA - DSM
$ 424
Kiwi
Pick dates

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.