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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in February , March 2026

12 Feb - 20 Mar $ 360.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
Pick dates
27 Feb - 20 Mar $ 383.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
Pick dates
27 Feb - 23 Mar $ 383.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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Last minute flights from Roanoke to Des Moines

12 Feb - 01 Mar $ 407.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
Pick dates
27 Feb - 01 Mar $ 431.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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19 Feb - 01 Mar $ 447.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
1 STOPS
ROA
Roanoke
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One-way flights to Des Moines from Roanoke

10:43 AM - 1:00 PM
United Airlines
1 Stops
4h 44m
ROA - DSM
$ 330
Kiwi
Pick dates
5:33 PM - 8:10 PM
United Airlines
1 Stops
5h 8m
ROA - DSM
$ 330
Kiwi
Pick dates
6:45 AM - 9:09 AM
United Airlines
1 Stops
5h 10m
ROA - DSM
$ 497
Kiwi
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.