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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in September , October 2026

27 Sep - 30 Oct $ 820.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
27 Sep - 01 Nov $ 856.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
27 Sep - 29 Oct $ 871.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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Last minute flights from Roanoke to Des Moines

27 Sep - 02 Oct $ 992.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
10 Sep - 02 Oct $ 1,103.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
27 Sep - 02 Oct $ 1,144.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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One-way flights to Des Moines from Roanoke

5:51 PM - 7:55 PM
United Airlines
1 Stops
4h 32m
ROA - DSM
$ 378
Kiwi
Pick dates
5:51 PM - 8:00 PM
United Airlines
1 Stops
4h 37m
ROA - DSM
$ 434
Kiwi
Pick dates
5:50 PM - 7:55 PM
United Airlines
1 Stops
4h 33m
ROA - DSM
$ 444
Kiwi
Pick dates

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.