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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in July , August 2026

30 Jul - 03 Aug $ 688.00
ROA
Roanoke
United Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
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30 Jul - 03 Aug $ 768.00
ROA
Roanoke
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
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30 Jul - 03 Aug $ 837.00
ROA
Roanoke
United Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
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Last minute flights from Roanoke to Des Moines

27 Jul - 02 Aug $ 942.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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27 Jul - 02 Aug $ 1,067.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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30 Jul - 02 Aug $ 1,417.00
ROA
Roanoke
Allegiant Air
3 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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One-way flights to Des Moines from Roanoke

5:52 PM - 7:45 PM
United Airlines
1 Stops
4h 30m
ROA - DSM
$ 424
Kiwi
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5:52 PM - 7:45 PM
United Airlines
1 Stops
4h 30m
ROA - DSM
$ 428
Kiwi
Pick dates
6:40 AM - 8:42 AM
United Airlines
1 Stops
4h 37m
ROA - DSM
$ 428
Kiwi
Pick dates

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.