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Cheap flights from Roanoke (ROA) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
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Cheap flights from Roanoke to Des Moines in April , May 2026

26 Apr - 26 May $ 409.00
ROA
Roanoke
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
Pick dates
26 Apr - 26 May $ 409.00
ROA
Roanoke
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
Pick dates
26 Apr - 26 May $ 409.00
ROA
Roanoke
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
ROA
Roanoke
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Last minute flights from Roanoke to Des Moines

17 Apr - 01 May $ 514.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
Pick dates
24 Apr - 01 May $ 520.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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10 Apr - 01 May $ 569.00
ROA
Roanoke
Allegiant Air
1 STOPS
DSM
Des Moines
DSM
Des Moines
Allegiant Air
3 STOPS
ROA
Roanoke
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One-way flights to Des Moines from Roanoke

5:45 PM - 8:00 PM
United Airlines
1 Stops
4h 47m
ROA - DSM
$ 361
Kiwi
Pick dates
10:48 AM - 12:59 PM
United Airlines
1 Stops
4h 37m
ROA - DSM
$ 381
Kiwi
Pick dates
6:45 AM - 9:05 AM
United Airlines
1 Stops
4h 59m
ROA - DSM
$ 381
Kiwi
Pick dates

How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Roanoke (ROA) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.