Earn point on your loyalty program!arrow arc left

Cheap flights from San Antonio (SAT) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)

How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from San Antonio to Des Moines in November , December 2025

28 Nov - 11 Dec $ 436.00
SAT
San Antonio
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
SAT
San Antonio
Pick dates
27 Nov - 04 Dec $ 485.00
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
Pick dates
27 Nov - 04 Dec $ 485.00
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
Pick dates

Last minute flights from San Antonio to Des Moines

28 Nov - 01 Dec $ 528.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
Pick dates
28 Nov - 01 Dec $ 549.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
SAT
San Antonio
Pick dates
28 Nov - 01 Dec $ 599.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
Pick dates

One-way flights to Des Moines from San Antonio

9:45 AM - 12:05 PM
United Airlines
1 Stops
4h 36m
SAT - DSM
$ 239
Kiwi
Pick dates
7:05 AM - 12:59 PM
United Airlines
1 Stops
7h 14m
SAT - DSM
$ 239
Kiwi
Pick dates
6:00 PM - 7:59 PM
United Airlines
1 Stops
4h 20m
SAT - DSM
$ 426
Kiwi
Pick dates

How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.