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Cheap flights from San Antonio (SAT) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)

How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
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How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
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How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
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Cheap flights from San Antonio to Des Moines in December 2025 , January 2026

30 Dec - 19 Jan $ 370.00
SAT
San Antonio
Spirit Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
SAT
San Antonio
Pick dates
30 Dec - 30 Jan $ 397.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
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30 Dec - 26 Jan $ 418.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
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Last minute flights from San Antonio to Des Moines

30 Dec - 01 Jan $ 560.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
SAT
San Antonio
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30 Dec - 01 Jan $ 638.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
SAT
San Antonio
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30 Dec - 01 Jan $ 646.00
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
SAT
San Antonio
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One-way flights to Des Moines from San Antonio

9:51 AM - 11:55 AM
United Airlines
1 Stops
4h 28m
SAT - DSM
$ 205
Kiwi
Pick dates
2:13 PM - 5:00 PM
United Airlines
1 Stops
5h 8m
SAT - DSM
$ 205
Kiwi
Pick dates
9:51 AM - 11:55 AM
United Airlines
1 Stops
4h 28m
SAT - DSM
$ 300
Kiwi
Pick dates

How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Antonio (SAT) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.