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Cheap flights from San Diego (SAN) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)

How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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Cheap flights from San Diego to Des Moines in January , February 2026

29 Jan - 15 Feb $ 212.00
SAN
San Diego
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SAN
San Diego
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16 Jan - 04 Feb $ 713.00
SAN
San Diego
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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16 Jan - 10 Feb $ 713.00
SAN
San Diego
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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Last minute flights from San Diego to Des Moines

24 Jan - 31 Jan $ 732.00
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
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24 Jan - 31 Jan $ 732.00
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
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16 Jan - 31 Jan $ 838.00
SAN
San Diego
Alaska Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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One-way flights to Des Moines from San Diego

6:30 AM - 7:53 PM
Allegiant Air
2 Stops
13h 39m
SAN - DSM
$ 143
Kiwi
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6:25 AM - 4:37 PM
Frontier Airlines
1 Stops
10h 58m
SAN - DSM
$ 271
Kiwi
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9:00 AM - 1:34 PM
United Airlines
1 Stops
5h 28m
SAN - DSM
$ 415
Kiwi
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.