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Cheap flights from San Diego (SAN) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)

How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
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Cheap flights from San Diego to Des Moines in April , May 2026

29 Apr - 05 May $ 427.00
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
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16 Apr - 06 May $ 672.00
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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16 Apr - 08 May $ 755.00
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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Last minute flights from San Diego to Des Moines

26 Apr - 30 Apr $ 577.00
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
Pick dates
15 Apr - 30 Apr $ 755.00
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
Pick dates
16 Apr - 30 Apr $ 755.00
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
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One-way flights to Des Moines from San Diego

8:45 AM - 1:25 PM
United Airlines
1 Stops
5h 25m
SAN - DSM
$ 224
Kiwi
Pick dates
12:15 PM - 10:29 PM
Alaska Airlines
1 Stops
9h 34m
SAN - DSM
$ 439
Kiwi
Pick dates
8:45 AM - 1:25 PM
United Airlines
1 Stops
5h 25m
SAN - DSM
$ 449
Kiwi
Pick dates

How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Diego (SAN) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.