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Cheap flights from San Francisco (SFO) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)

How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)
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How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)
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How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)
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Cheap flights from San Francisco to Des Moines in April , May 2026

17 Apr - 01 May $ 377.00
SFO
San Francisco
Frontier Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
SFO
San Francisco
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08 Apr - 01 May $ 1,081.00
SFO
San Francisco
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
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12 Apr - 01 May $ 2,601.00
SFO
San Francisco
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
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Last minute flights from San Francisco to Des Moines

23 Apr - 30 Apr $ 499.00
SFO
San Francisco
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
SFO
San Francisco
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08 Apr - 30 Apr $ 1,081.00
SFO
San Francisco
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
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12 Apr - 30 Apr $ 2,601.00
SFO
San Francisco
Alaska Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
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One-way flights to Des Moines from San Francisco

12:23 PM - 4:29 PM
Allegiant Air
1 Stops
7h 1m
SFO - DSM
$ 227
Kiwi
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5:00 AM - 9:45 AM
United Airlines
1 Stops
5h 47m
SFO - DSM
$ 469
Kiwi
Pick dates
5:00 AM - 9:45 AM
United Airlines
1 Stops
5h 47m
SFO - DSM
$ 469
Kiwi
Pick dates

How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.