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Cheap flights from St Louis (STL) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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Cheap flights from St Louis to Des Moines in April , May 2026

24 Apr - 28 May $ 321.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
STL
St Louis
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24 Apr - 28 May $ 344.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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30 Apr - 04 May $ 488.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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Last minute flights from St Louis to Des Moines

28 Apr - 30 Apr $ 529.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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27 Apr - 30 Apr $ 529.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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28 Apr - 30 Apr $ 529.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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One-way flights to Des Moines from St Louis

7:45 AM - 10:52 AM
United Airlines
1 Stops
4h 44m
STL - DSM
$ 225
Kiwi
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9:10 AM - 12:59 PM
United Airlines
1 Stops
5h 15m
STL - DSM
$ 225
Kiwi
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6:30 AM - 9:01 AM
United Airlines
1 Stops
4h 7m
STL - DSM
$ 245
Kiwi
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.