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Cheap flights from St Louis (STL) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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Cheap flights from St Louis to Des Moines in April , May 2026

30 Apr - 01 May $ 377.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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30 Apr - 01 May $ 377.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
Pick dates
30 Apr - 01 May $ 377.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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Last minute flights from St Louis to Des Moines

24 Apr - 01 May $ 365.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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17 Apr - 01 May $ 365.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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24 Apr - 30 Apr $ 385.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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One-way flights to Des Moines from St Louis

6:55 PM - 9:40 PM
United Airlines
1 Stops
4h 22m
STL - DSM
$ 185
Kiwi
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6:30 AM - 9:05 AM
United Airlines
1 Stops
4h 14m
STL - DSM
$ 211
Kiwi
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8:21 AM - 10:52 AM
United Airlines
1 Stops
4h 8m
STL - DSM
$ 226
Kiwi
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.