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Cheap flights from St Louis (STL) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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Cheap flights from St Louis to Des Moines in September , October 2026

30 Sep - 26 Oct $ 293.00
STL
St Louis
Southern Airways Express
2 STOPS
DSM
Des Moines
DSM
Des Moines
Southern Airways Express
2 STOPS
STL
St Louis
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30 Sep - 25 Oct $ 341.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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16 Sep - 25 Oct $ 351.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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Last minute flights from St Louis to Des Moines

16 Sep - 01 Oct $ 443.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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16 Sep - 01 Oct $ 454.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
1 STOPS
STL
St Louis
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23 Sep - 01 Oct $ 461.00
STL
St Louis
Frontier Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Frontier Airlines
2 STOPS
STL
St Louis
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One-way flights to Des Moines from St Louis

5:36 PM - 7:55 PM
United Airlines
1 Stops
3h 47m
STL - DSM
$ 201
Kiwi
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8:30 AM - 12:54 PM
United Airlines
1 Stops
5h 50m
STL - DSM
$ 295
Kiwi
Pick dates
5:30 PM - 8:00 PM
United Airlines
1 Stops
3h 58m
STL - DSM
$ 296
Kiwi
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.