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Cheap flights from St Louis (STL) to Des Moines (DSM)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
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Cheap flights from St Louis to Des Moines in December 2025 , January 2026

30 Dec - 06 Jan $ 285.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
Pick dates
30 Dec - 06 Jan $ 285.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
Pick dates
30 Dec - 06 Jan $ 285.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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Last minute flights from St Louis to Des Moines

29 Dec - 31 Dec $ 406.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
Pick dates
29 Dec - 31 Dec $ 406.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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29 Dec - 31 Dec $ 406.00
STL
St Louis
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
STL
St Louis
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One-way flights to Des Moines from St Louis

6:30 AM - 9:02 AM
United Airlines
1 Stops
4h 20m
STL - DSM
$ 160
Kiwi
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3:10 PM - 6:05 PM
United Airlines
1 Stops
4h 19m
STL - DSM
$ 275
Kiwi
Pick dates
2:45 PM - 5:42 PM
United Airlines
1 Stops
5h 45m
STL - DSM
$ 275
Kiwi
Pick dates

How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)

Related info for your journey
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How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.