Earn point on your loyalty program!arrow arc left

Cheap flights from West Palm Beach (PBI) to Des Moines (DSM)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)

How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from West Palm Beach to Des Moines in November , December 2025

26 Nov - 08 Dec $ 466.00
PBI
West Palm Beach
Spirit Airlines
2 STOPS
DSM
Des Moines
DSM
Des Moines
Spirit Airlines
1 STOPS
PBI
West Palm Beach
Pick dates
27 Nov - 01 Dec $ 579.00
PBI
West Palm Beach
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PBI
West Palm Beach
Pick dates
27 Nov - 01 Dec $ 579.00
PBI
West Palm Beach
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PBI
West Palm Beach
Pick dates

Last minute flights from West Palm Beach to Des Moines

23 Nov - 30 Nov $ 875.00
PBI
West Palm Beach
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PBI
West Palm Beach
Pick dates
23 Nov - 30 Nov $ 875.00
PBI
West Palm Beach
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PBI
West Palm Beach
Pick dates
23 Nov - 30 Nov $ 875.00
PBI
West Palm Beach
United Airlines
1 STOPS
DSM
Des Moines
DSM
Des Moines
United Airlines
1 STOPS
PBI
West Palm Beach
Pick dates

One-way flights to Des Moines from West Palm Beach

6:30 AM - 12:05 PM
United Airlines
1 Stops
8h 51m
PBI - DSM
$ 228
Kiwi
Pick dates
6:30 AM - 11:55 AM
United Airlines
1 Stops
8h 41m
PBI - DSM
$ 353
Kiwi
Pick dates
7:30 AM - 10:40 AM
United Airlines
1 Stops
5h 44m
PBI - DSM
$ 405
Kiwi
Pick dates

How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from West Palm Beach (PBI) to Des Moines (DSM)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.