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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in April , May 2026

30 Apr - 29 May $ 361.00
CHI
Chicago
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CHI
Chicago
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17 Apr - 07 May $ 470.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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10 Apr - 05 May $ 572.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

26 Apr - 01 May $ 471.00
CHI
Chicago
Spirit Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Spirit Airlines
1 STOPS
CHI
Chicago
Pick dates
13 Apr - 30 Apr $ 993.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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10 Apr - 30 Apr $ 1,612.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

10:37 AM - 7:45 PM
Spirit Airlines
1 Stops
12h 27m
CHI - GYE
$ 150
Kiwi
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11:20 PM - 6:55 AM
Avianca
1 Stops
9h 35m
CHI - GYE
$ 184
Kiwi
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3:05 PM - 9:24 PM
Copa Airlines
1 Stops
8h 33m
CHI - GYE
$ 246
Kiwi
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.