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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in August , September 2026

24 Aug - 10 Sep $ 609.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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28 Aug - 16 Sep $ 652.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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24 Aug - 09 Sep $ 843.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

27 Aug - 31 Aug $ 741.00
CHI
Chicago
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
CHI
Chicago
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26 Aug - 31 Aug $ 938.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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26 Aug - 31 Aug $ 1,371.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

10:35 AM - 9:24 PM
United Airlines
2 Stops
13h 3m
CHI - GYE
$ 320
Kiwi
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3:21 PM - 9:24 PM
Copa Airlines
1 Stops
8h 17m
CHI - GYE
$ 366
Kiwi
Pick dates
3:21 PM - 9:24 PM
Copa Airlines
1 Stops
8h 17m
CHI - GYE
$ 366
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.