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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in March , April 2026

02 Mar - 01 Apr $ 398.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
Pick dates
05 Mar - 27 Apr $ 403.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
Pick dates
06 Mar - 10 Apr $ 510.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

29 Mar - 31 Mar $ 408.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
Pick dates
03 Mar - 31 Mar $ 419.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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06 Mar - 31 Mar $ 752.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

2:22 PM - 9:40 PM
Copa Airlines
1 Stops
8h 33m
CHI - GYE
$ 167
Kiwi
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10:20 PM - 7:20 AM
Avianca
1 Stops
9h 55m
CHI - GYE
$ 173
Kiwi
Pick dates
2:22 PM - 9:24 PM
Copa Airlines
1 Stops
8h 19m
CHI - GYE
$ 183
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.