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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in May , June 2026

26 May - 05 Jun $ 510.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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21 May - 08 Jun $ 697.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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17 May - 06 Jun $ 821.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

22 May - 01 Jun $ 830.00
CHI
Chicago
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
CHI
Chicago
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21 May - 01 Jun $ 930.00
CHI
Chicago
JetBlue Airways
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
CHI
Chicago
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17 May - 31 May $ 1,850.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

5:45 PM - 6:55 AM
Avianca
2 Stops
15h 10m
CHI - GYE
$ 272
Kiwi
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9:05 AM - 9:24 PM
United Airlines
2 Stops
14h 31m
CHI - GYE
$ 275
Kiwi
Pick dates
9:05 AM - 9:24 PM
United Airlines
2 Stops
14h 31m
CHI - GYE
$ 275
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.