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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in June , July 2026

20 Jun - 17 Jul $ 561.00
CHI
Chicago
JetBlue Airways
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
CHI
Chicago
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13 Jun - 09 Jul $ 645.00
CHI
Chicago
JetBlue Airways
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
CHI
Chicago
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13 Jun - 04 Jul $ 826.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

20 Jun - 30 Jun $ 688.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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13 Jun - 30 Jun $ 768.00
CHI
Chicago
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
1 STOPS
CHI
Chicago
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13 Jun - 30 Jun $ 1,718.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

11:27 AM - 9:48 PM
Copa Airlines
2 Stops
12h 34m
CHI - GYE
$ 259
Kiwi
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6:30 AM - 3:17 PM
United Airlines
2 Stops
10h 59m
CHI - GYE
$ 277
Kiwi
Pick dates
3:21 PM - 9:24 PM
Copa Airlines
1 Stops
8h 15m
CHI - GYE
$ 288
Kiwi
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.