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Cheap flights from Chicago (CHI) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
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Cheap flights from Chicago to Guayaquil in September , October 2026

28 Sep - 13 Oct $ 734.00
CHI
Chicago
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
CHI
Chicago
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28 Sep - 26 Oct $ 771.00
CHI
Chicago
Copa Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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28 Sep - 12 Oct $ 1,305.00
CHI
Chicago
United Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Guayaquil

28 Sep - 30 Sep $ 876.00
CHI
Chicago
Copa Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
2 STOPS
CHI
Chicago
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28 Sep - 01 Oct $ 921.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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29 Sep - 30 Sep $ 1,287.00
CHI
Chicago
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
CHI
Chicago
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One-way flights to Guayaquil from Chicago

5:30 AM - 3:17 PM
United Airlines
2 Stops
12h
CHI - GYE
$ 340
Kiwi
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5:00 AM - 9:24 PM
United Airlines
2 Stops
18h 37m
CHI - GYE
$ 340
Kiwi
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10:55 AM - 9:24 PM
United Airlines
2 Stops
12h 42m
CHI - GYE
$ 362
Kiwi
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.