Earn point on your loyalty program!arrow arc left

Cheap flights from Cleveland (CLE) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)

How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Cleveland to Guayaquil in April , May 2026

20 Apr - 08 May $ 383.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates
27 Apr - 08 May $ 384.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates
26 Apr - 08 May $ 384.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates

Last minute flights from Cleveland to Guayaquil

27 Apr - 01 May $ 457.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates
20 Apr - 01 May $ 457.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates
26 Apr - 01 May $ 457.00
CLE
Cleveland
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
1 STOPS
CLE
Cleveland
Pick dates

One-way flights to Guayaquil from Cleveland

7:00 AM - 7:45 PM
Spirit Airlines
1 Stops
17h 4m
CLE - GYE
$ 162
Kiwi
Pick dates
6:15 AM - 7:45 PM
Spirit Airlines
1 Stops
17h 49m
CLE - GYE
$ 162
Kiwi
Pick dates
7:00 AM - 7:45 PM
Spirit Airlines
1 Stops
17h 4m
CLE - GYE
$ 162
Kiwi
Pick dates

How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.