Earn point on your loyalty program!arrow arc left

Cheap flights from Columbus (CMH) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)

How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Columbus to Guayaquil in April , May 2026

26 Apr - 22 May $ 370.00
CMH
Columbus
Allegiant Air
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
1 STOPS
CMH
Columbus
Pick dates
26 Apr - 29 May $ 370.00
CMH
Columbus
Allegiant Air
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
1 STOPS
CMH
Columbus
Pick dates
30 Apr - 22 May $ 378.00
CMH
Columbus
Allegiant Air
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
1 STOPS
CMH
Columbus
Pick dates

Last minute flights from Columbus to Guayaquil

26 Apr - 01 May $ 473.00
CMH
Columbus
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
CMH
Columbus
Pick dates
26 Apr - 01 May $ 549.00
CMH
Columbus
Allegiant Air
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
1 STOPS
CMH
Columbus
Pick dates
27 Apr - 01 May $ 555.00
CMH
Columbus
Allegiant Air
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
1 STOPS
CMH
Columbus
Pick dates

One-way flights to Guayaquil from Columbus

6:00 AM - 7:45 PM
Spirit Airlines
1 Stops
18h 4m
CMH - GYE
$ 152
Kiwi
Pick dates
6:00 AM - 7:45 PM
Spirit Airlines
1 Stops
18h 4m
CMH - GYE
$ 166
Kiwi
Pick dates
6:00 AM - 7:45 PM
Spirit Airlines
1 Stops
18h 4m
CMH - GYE
$ 194
Kiwi
Pick dates

How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Columbus (CMH) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.