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Cheap flights from Detroit (DTW) to Guayaquil (GYE)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)

How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)
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How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)
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How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)
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Cheap flights from Detroit to Guayaquil in April , May 2026

12 Apr - 03 May $ 427.00
DTW
Detroit
Spirit Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Spirit Airlines
1 STOPS
DTW
Detroit
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14 Apr - 02 May $ 444.00
DTW
Detroit
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
DTW
Detroit
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12 Apr - 02 May $ 445.00
DTW
Detroit
Frontier Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
DTW
Detroit
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Last minute flights from Detroit to Guayaquil

12 Apr - 01 May $ 459.00
DTW
Detroit
Spirit Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Spirit Airlines
1 STOPS
DTW
Detroit
Pick dates
14 Apr - 01 May $ 461.00
DTW
Detroit
Spirit Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Spirit Airlines
2 STOPS
DTW
Detroit
Pick dates
12 Apr - 01 May $ 462.00
DTW
Detroit
Spirit Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Spirit Airlines
2 STOPS
DTW
Detroit
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One-way flights to Guayaquil from Detroit

2:29 PM - 7:45 PM
Spirit Airlines
1 Stops
9h 35m
DTW - GYE
$ 193
Kiwi
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7:00 AM - 11:30 PM
LATAM Airlines
2 Stops
19h 40m
DTW - GYE
$ 558
Kiwi
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1:45 PM - 9:24 PM
United Airlines
2 Stops
10h 53m
DTW - GYE
$ 2,709
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.