Earn point on your loyalty program!arrow arc left

Cheap flights from Mcallen (MFE) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)

How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Mcallen to Guayaquil in November , December 2025

26 Nov - 11 Dec $ 577.00
MFE
Mcallen
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
MFE
Mcallen
Pick dates
25 Nov - 11 Dec $ 577.00
MFE
Mcallen
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
MFE
Mcallen
Pick dates
26 Nov - 11 Dec $ 577.00
MFE
Mcallen
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
MFE
Mcallen
Pick dates

One-way flights to Guayaquil from Mcallen

7:00 AM - 3:25 PM
United Airlines
2 Stops
9h 42m
MFE - GYE
$ 639
Kiwi
Pick dates
7:00 AM - 3:25 PM
United Airlines
2 Stops
9h 42m
MFE - GYE
$ 639
Kiwi
Pick dates
12:15 PM - 9:24 PM
United Airlines
2 Stops
10h 26m
MFE - GYE
$ 639
Kiwi
Pick dates

How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.