Earn point on your loyalty program!arrow arc left

Cheap flights from Medford (MFR) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)

How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Medford to Guayaquil in May , June 2026

28 May - 19 Jun $ 810.00
MFR
Medford
Allegiant Air
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
2 STOPS
MFR
Medford
Pick dates
28 May - 24 Jun $ 831.00
MFR
Medford
Alaska Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Alaska Airlines
3 STOPS
MFR
Medford
Pick dates
28 May - 08 Jun $ 831.00
MFR
Medford
Allegiant Air
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Allegiant Air
2 STOPS
MFR
Medford
Pick dates

Last minute flights from Medford to Guayaquil

28 May - 01 Jun $ 904.00
MFR
Medford
Alaska Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Alaska Airlines
3 STOPS
MFR
Medford
Pick dates
28 May - 01 Jun $ 973.00
MFR
Medford
Alaska Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Alaska Airlines
3 STOPS
MFR
Medford
Pick dates
27 May - 01 Jun $ 986.00
MFR
Medford
Alaska Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Alaska Airlines
3 STOPS
MFR
Medford
Pick dates

One-way flights to Guayaquil from Medford

6:35 AM - 6:55 AM
Avianca
3 Stops
24h 20m
MFR - GYE
$ 384
Kiwi
Pick dates
1:26 PM - 9:08 AM
Copa Airlines
3 Stops
19h 54m
MFR - GYE
$ 466
Kiwi
Pick dates
12:48 PM - 6:55 AM
Avianca
3 Stops
18h 7m
MFR - GYE
$ 489
Kiwi
Pick dates

How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Medford (MFR) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.