Earn point on your loyalty program!arrow arc left

Cheap flights from Raleigh Durham (RDU) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)

How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Raleigh Durham to Guayaquil in November , December 2026

23 Nov - 15 Dec $ 452.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates
14 Nov - 04 Dec $ 634.00
RDU
Raleigh Durham
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
14 Nov - 07 Dec $ 811.00
RDU
Raleigh Durham
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates

Last minute flights from Raleigh Durham to Guayaquil

23 Nov - 01 Dec $ 555.00
RDU
Raleigh Durham
JetBlue Airways
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
RDU
Raleigh Durham
Pick dates
23 Nov - 01 Dec $ 575.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates
14 Nov - 01 Dec $ 702.00
RDU
Raleigh Durham
JetBlue Airways
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
RDU
Raleigh Durham
Pick dates

One-way flights to Guayaquil from Raleigh Durham

6:30 AM - 12:00 PM
JetBlue Airways
1 Stops
9h 59m
RDU - GYE
$ 315
Kiwi
Pick dates
6:30 AM - 12:00 PM
JetBlue Airways
1 Stops
9h 59m
RDU - GYE
$ 327
Kiwi
Pick dates
6:30 AM - 12:00 PM
JetBlue Airways
1 Stops
9h 59m
RDU - GYE
$ 375
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.