Earn point on your loyalty program!arrow arc left

Cheap flights from San Francisco (SFO) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)

How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from San Francisco to Guayaquil in August , September 2026

27 Aug - 09 Sep $ 674.00
SFO
San Francisco
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
SFO
San Francisco
Pick dates
23 Aug - 08 Sep $ 784.00
SFO
San Francisco
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
2 STOPS
SFO
San Francisco
Pick dates
27 Aug - 06 Sep $ 1,082.00
SFO
San Francisco
Copa Airlines
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Copa Airlines
1 STOPS
SFO
San Francisco
Pick dates

Last minute flights from San Francisco to Guayaquil

24 Aug - 31 Aug $ 780.00
SFO
San Francisco
United Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
United Airlines
2 STOPS
SFO
San Francisco
Pick dates
27 Aug - 01 Sep $ 818.00
SFO
San Francisco
Avianca
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
Avianca
2 STOPS
SFO
San Francisco
Pick dates
27 Aug - 31 Aug $ 1,139.00
SFO
San Francisco
JetBlue Airways
1 STOPS
GYE
Guayaquil
GYE
Guayaquil
JetBlue Airways
1 STOPS
SFO
San Francisco
Pick dates

One-way flights to Guayaquil from San Francisco

7:05 AM - 9:24 PM
United Airlines
2 Stops
14h 33m
SFO - GYE
$ 366
Kiwi
Pick dates
12:45 AM - 3:17 PM
United Airlines
2 Stops
14h 46m
SFO - GYE
$ 366
Kiwi
Pick dates
1:12 AM - 11:21 AM
Copa Airlines
1 Stops
10h 23m
SFO - GYE
$ 447
Kiwi
Pick dates

How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.