Earn point on your loyalty program!arrow arc left

Cheap flights from St Louis (STL) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from St Louis to Guayaquil in November , December 2026

25 Nov - 16 Dec $ 804.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
25 Nov - 02 Dec $ 806.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
27 Nov - 01 Dec $ 820.00
STL
St Louis
Frontier Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates

Last minute flights from St Louis to Guayaquil

25 Nov - 01 Dec $ 958.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
25 Nov - 01 Dec $ 973.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
25 Nov - 01 Dec $ 978.00
STL
St Louis
Southern Airways Express
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Southern Airways Express
3 STOPS
STL
St Louis
Pick dates

One-way flights to Guayaquil from St Louis

6:35 PM - 12:05 PM
JetBlue Airways
3 Stops
20h 59m
STL - GYE
$ 478
Kiwi
Pick dates
6:35 PM - 11:27 AM
Copa Airlines
3 Stops
18h 7m
STL - GYE
$ 483
Kiwi
Pick dates
6:09 PM - 9:02 AM
Copa Airlines
3 Stops
16h 9m
STL - GYE
$ 524
Kiwi
Pick dates

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.