Earn point on your loyalty program!arrow arc left

Cheap flights from St Louis (STL) to Guayaquil (GYE)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from St Louis to Guayaquil in September , October 2026

30 Sep - 30 Oct $ 860.00
STL
St Louis
Frontier Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
30 Sep - 30 Oct $ 862.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
30 Sep - 30 Oct $ 913.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
3 STOPS
STL
St Louis
Pick dates

Last minute flights from St Louis to Guayaquil

28 Sep - 01 Oct $ 1,235.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
3 STOPS
STL
St Louis
Pick dates
28 Sep - 01 Oct $ 1,252.00
STL
St Louis
Frontier Airlines
3 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
2 STOPS
STL
St Louis
Pick dates
28 Sep - 01 Oct $ 1,315.00
STL
St Louis
Frontier Airlines
2 STOPS
GYE
Guayaquil
GYE
Guayaquil
Frontier Airlines
3 STOPS
STL
St Louis
Pick dates

One-way flights to Guayaquil from St Louis

8:10 PM - 6:39 PM
Copa Airlines
3 Stops
24h 42m
STL - GYE
$ 542
Kiwi
Pick dates
2:29 PM - 12:00 PM
JetBlue Airways
2 Stops
24h 55m
STL - GYE
$ 551
Kiwi
Pick dates
2:29 PM - 9:08 AM
Copa Airlines
3 Stops
20h 52m
STL - GYE
$ 553
Kiwi
Pick dates

How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Guayaquil (GYE)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.