Earn point on your loyalty program!arrow arc left

Cheap flights from Knoxville (TYS) to Indianapolis (IND)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)

How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Knoxville to Indianapolis in November , December 2026

17 Nov - 06 Dec $ 217.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates
17 Nov - 31 Dec $ 236.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates
17 Nov - 02 Dec $ 238.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates

Last minute flights from Knoxville to Indianapolis

17 Nov - 30 Nov $ 330.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates
17 Nov - 30 Nov $ 376.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates
12 Nov - 30 Nov $ 513.00
TYS
Knoxville
Allegiant Air
1 STOPS
IND
Indianapolis
IND
Indianapolis
Allegiant Air
1 STOPS
TYS
Knoxville
Pick dates

One-way flights to Indianapolis from Knoxville

6:08 PM - 9:00 AM
Frontier Airlines
1 Stops
17h 45m
TYS - IND
$ 112
Kiwi
Pick dates
9:13 PM - 8:30 AM
Allegiant Air
1 Stops
14h 5m
TYS - IND
$ 191
Kiwi
Pick dates
2:09 PM - 4:37 PM
Allegiant Air
1 Stops
5h 25m
TYS - IND
$ 260
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Indianapolis (IND)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.