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Cheap flights from Des Moines (DSM) to Jacksonville (JAX)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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Cheap flights from Des Moines to Jacksonville in January , February 2026

27 Jan - 03 Feb $ 492.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
27 Jan - 03 Feb $ 492.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
27 Jan - 03 Feb $ 492.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

Last minute flights from Des Moines to Jacksonville

27 Jan - 31 Jan $ 567.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
27 Jan - 31 Jan $ 567.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
27 Jan - 31 Jan $ 567.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

One-way flights to Jacksonville from Des Moines

8:00 AM - 10:35 AM
United Airlines
1 Stops
5h 9m
DSM - JAX
$ 284
Kiwi
Pick dates
3:35 PM - 6:06 PM
United Airlines
1 Stops
5h 9m
DSM - JAX
$ 399
Kiwi
Pick dates
8:00 AM - 10:35 AM
United Airlines
1 Stops
5h 9m
DSM - JAX
$ 399
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.