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Cheap flights from Des Moines (DSM) to Jacksonville (JAX)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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Cheap flights from Des Moines to Jacksonville in August , September 2026

31 Aug - 01 Oct $ 334.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
1 STOPS
DSM
Des Moines
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31 Aug - 24 Sep $ 391.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
31 Aug - 20 Sep $ 396.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to Jacksonville

27 Aug - 01 Sep $ 726.00
DSM
Des Moines
WestJet
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
WestJet
3 STOPS
DSM
Des Moines
Pick dates
27 Aug - 01 Sep $ 741.00
DSM
Des Moines
WestJet
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
WestJet
3 STOPS
DSM
Des Moines
Pick dates
27 Aug - 01 Sep $ 848.00
DSM
Des Moines
WestJet
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
WestJet
3 STOPS
DSM
Des Moines
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One-way flights to Jacksonville from Des Moines

6:30 AM - 4:54 PM
Frontier Airlines
2 Stops
10h 40m
DSM - JAX
$ 213
Kiwi
Pick dates
1:21 PM - 3:50 PM
United Airlines
1 Stops
5h 4m
DSM - JAX
$ 444
Kiwi
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8:00 AM - 10:29 AM
United Airlines
1 Stops
5h 4m
DSM - JAX
$ 444
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.