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Cheap flights from Des Moines (DSM) to Jacksonville (JAX)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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Cheap flights from Des Moines to Jacksonville in September , October 2026

28 Sep - 05 Oct $ 493.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
28 Sep - 05 Oct $ 493.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
28 Sep - 05 Oct $ 493.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

Last minute flights from Des Moines to Jacksonville

28 Sep - 01 Oct $ 291.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
27 Sep - 01 Oct $ 297.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
27 Sep - 01 Oct $ 313.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates

One-way flights to Jacksonville from Des Moines

3:11 PM - 6:05 PM
United Airlines
1 Stops
5h 36m
DSM - JAX
$ 247
Kiwi
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11:32 AM - 2:05 PM
United Airlines
1 Stops
5h 17m
DSM - JAX
$ 454
Kiwi
Pick dates
8:00 AM - 10:30 AM
United Airlines
1 Stops
5h 5m
DSM - JAX
$ 529
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.