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Cheap flights from Des Moines (DSM) to Jacksonville (JAX)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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Cheap flights from Des Moines to Jacksonville in February , March 2026

28 Feb - 28 Mar $ 453.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
28 Feb - 28 Mar $ 453.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Feb - 02 Mar $ 461.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to Jacksonville

20 Feb - 28 Feb $ 532.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
21 Feb - 28 Feb $ 532.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
20 Feb - 28 Feb $ 532.00
DSM
Des Moines
United Airlines
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
United Airlines
1 STOPS
DSM
Des Moines
Pick dates

One-way flights to Jacksonville from Des Moines

3:24 PM - 5:57 PM
United Airlines
1 Stops
5h
DSM - JAX
$ 208
Kiwi
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3:24 PM - 5:57 PM
United Airlines
1 Stops
5h
DSM - JAX
$ 398
Kiwi
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8:30 AM - 6:00 AM
BREEZE
3 Stops
23h 24m
DSM - JAX
$ 887
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.