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Cheap flights from Des Moines (DSM) to Jacksonville (JAX)

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0 Children (2~11)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
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Cheap flights from Des Moines to Jacksonville in May , June 2026

24 May - 04 Jun $ 304.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
DIRECT
DSM
Des Moines
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24 May - 18 Jun $ 311.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
DIRECT
DSM
Des Moines
Pick dates
24 May - 25 Jun $ 314.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
DIRECT
DSM
Des Moines
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Last minute flights from Des Moines to Jacksonville

28 May - 01 Jun $ 398.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
24 May - 01 Jun $ 407.00
DSM
Des Moines
Allegiant Air
2 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
24 May - 01 Jun $ 441.00
DSM
Des Moines
Allegiant Air
1 STOPS
JAX
Jacksonville
JAX
Jacksonville
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates

One-way flights to Jacksonville from Des Moines

11:18 AM - 1:55 PM
United Airlines
1 Stops
5h 26m
DSM - JAX
$ 259
Kiwi
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8:00 AM - 10:42 AM
United Airlines
1 Stops
5h 27m
DSM - JAX
$ 259
Kiwi
Pick dates
11:40 AM - 2:00 PM
United Airlines
1 Stops
5h 5m
DSM - JAX
$ 507
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to Jacksonville (JAX)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.