Earn point on your loyalty program!arrow arc left

Cheap flights from Knoxville (TYS) to Manchester (MAN)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)

How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Knoxville to Manchester in April , May 2026

28 Apr - 08 May $ 998.00
TYS
Knoxville
United Airlines
2 STOPS
MAN
Manchester
MAN
Manchester
United Airlines
2 STOPS
TYS
Knoxville
Pick dates
29 Apr - 07 May $ 998.00
TYS
Knoxville
United Airlines
2 STOPS
MAN
Manchester
MAN
Manchester
United Airlines
2 STOPS
TYS
Knoxville
Pick dates
14 Apr - 05 May $ 1,653.00
TYS
Knoxville
Aer Lingus
2 STOPS
MAN
Manchester
MAN
Manchester
Aer Lingus
2 STOPS
TYS
Knoxville
Pick dates

Last minute flights from Knoxville to Manchester

23 Apr - 30 Apr $ 1,045.00
TYS
Knoxville
United Airlines
2 STOPS
MAN
Manchester
MAN
Manchester
United Airlines
2 STOPS
TYS
Knoxville
Pick dates
14 Apr - 01 May $ 1,883.00
TYS
Knoxville
Aer Lingus
2 STOPS
MAN
Manchester
MAN
Manchester
Aer Lingus
2 STOPS
TYS
Knoxville
Pick dates
06 Apr - 30 Apr $ 2,081.00
TYS
Knoxville
Aer Lingus
2 STOPS
MAN
Manchester
MAN
Manchester
Aer Lingus
2 STOPS
TYS
Knoxville
Pick dates

One-way flights to Manchester from Knoxville

11:27 AM - 8:00 AM
Icelandair
2 Stops
19h 13m
TYS - MAN
$ 359
Kiwi
Pick dates
9:40 AM - 10:00 AM
United Airlines
2 Stops
19h 45m
TYS - MAN
$ 600
Kiwi
Pick dates
2:25 PM - 8:45 AM
United Airlines
2 Stops
14h 25m
TYS - MAN
$ 601
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Manchester (MAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.