Earn point on your loyalty program!arrow arc left

Cheap flights from Chicago (CHI) to Palermo (PMO)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)

How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Chicago to Palermo in March , April 2026

22 Mar - 28 Apr $ 937.00
CHI
Chicago
Aer Lingus
2 STOPS
PMO
Palermo
PMO
Palermo
Aer Lingus
2 STOPS
CHI
Chicago
Pick dates
22 Mar - 28 Apr $ 945.00
CHI
Chicago
Aer Lingus
2 STOPS
PMO
Palermo
PMO
Palermo
Aer Lingus
2 STOPS
CHI
Chicago
Pick dates
22 Mar - 27 Apr $ 949.00
CHI
Chicago
Aer Lingus
2 STOPS
PMO
Palermo
PMO
Palermo
Aer Lingus
2 STOPS
CHI
Chicago
Pick dates

Last minute flights from Chicago to Palermo

22 Mar - 01 Apr $ 662.00
CHI
Chicago
TAP Portugal
2 STOPS
PMO
Palermo
PMO
Palermo
TAP Portugal
2 STOPS
CHI
Chicago
Pick dates
10 Mar - 01 Apr $ 1,270.00
CHI
Chicago
TAP Portugal
2 STOPS
PMO
Palermo
PMO
Palermo
TAP Portugal
2 STOPS
CHI
Chicago
Pick dates
10 Mar - 01 Apr $ 1,270.00
CHI
Chicago
TAP Portugal
2 STOPS
PMO
Palermo
PMO
Palermo
TAP Portugal
2 STOPS
CHI
Chicago
Pick dates

One-way flights to Palermo from Chicago

9:25 PM - 9:40 PM
Aeroitalia
2 Stops
19h 25m
CHI - PMO
$ 425
Kiwi
Pick dates
9:25 PM - 9:40 PM
Aeroitalia
2 Stops
19h 25m
CHI - PMO
$ 489
Kiwi
Pick dates
7:30 PM - 5:20 PM
ITA Airways
2 Stops
16h 55m
CHI - PMO
$ 682
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Palermo (PMO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.