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Cheap flights from Des Moines (DSM) to San Antonio (SAT)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)

How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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Cheap flights from Des Moines to San Antonio in February , March 2026

27 Feb - 28 Mar $ 195.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
27 Feb - 28 Mar $ 221.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
22 Feb - 28 Mar $ 301.00
DSM
Des Moines
Frontier Airlines
2 STOPS
SAT
San Antonio
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Antonio

27 Feb - 01 Mar $ 383.00
DSM
Des Moines
Allegiant Air
2 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
2 STOPS
DSM
Des Moines
Pick dates
22 Feb - 01 Mar $ 416.00
DSM
Des Moines
Allegiant Air
2 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
2 STOPS
DSM
Des Moines
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24 Feb - 28 Feb $ 619.00
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
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One-way flights to San Antonio from Des Moines

2:59 PM - 6:40 PM
United Airlines
1 Stops
4h 54m
DSM - SAT
$ 229
Kiwi
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3:39 PM - 3:45 PM
Frontier Airlines
2 Stops
27h 22m
DSM - SAT
$ 315
Kiwi
Pick dates
3:04 PM - 6:30 PM
United Airlines
1 Stops
4h 37m
DSM - SAT
$ 469
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.