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Cheap flights from Des Moines (DSM) to San Antonio (SAT)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)

How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
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Cheap flights from Des Moines to San Antonio in March , April 2026

21 Mar - 13 Apr $ 229.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
Frontier Airlines
1 STOPS
DSM
Des Moines
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21 Mar - 16 Apr $ 245.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
28 Mar - 16 Apr $ 245.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Antonio

24 Mar - 31 Mar $ 387.00
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Mar - 31 Mar $ 387.00
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
Pick dates
24 Mar - 31 Mar $ 387.00
DSM
Des Moines
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
DSM
Des Moines
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One-way flights to San Antonio from Des Moines

8:21 PM - 5:45 AM
Frontier Airlines
1 Stops
12h 45m
DSM - SAT
$ 98
Kiwi
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1:30 PM - 9:50 PM
United Airlines
2 Stops
9h 27m
DSM - SAT
$ 354
Kiwi
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2:59 PM - 6:35 PM
United Airlines
1 Stops
4h 49m
DSM - SAT
$ 404
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.