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Cheap flights from Knoxville (TYS) to San Antonio (SAT)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)

How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)
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How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)
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How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)
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Cheap flights from Knoxville to San Antonio in December 2025 , January 2026

25 Dec - 07 Jan $ 313.00
TYS
Knoxville
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
25 Dec - 07 Jan $ 313.00
TYS
Knoxville
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
25 Dec - 08 Jan $ 313.00
TYS
Knoxville
United Airlines
1 STOPS
SAT
San Antonio
SAT
San Antonio
United Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to San Antonio

25 Dec - 31 Dec $ 520.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
1 STOPS
TYS
Knoxville
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30 Dec - 31 Dec $ 535.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
1 STOPS
TYS
Knoxville
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29 Dec - 31 Dec $ 579.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAT
San Antonio
SAT
San Antonio
Allegiant Air
1 STOPS
TYS
Knoxville
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One-way flights to San Antonio from Knoxville

7:00 AM - 12:00 PM
United Airlines
1 Stops
7h 11m
TYS - SAT
$ 144
Kiwi
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7:00 AM - 9:32 AM
United Airlines
1 Stops
4h 40m
TYS - SAT
$ 225
Kiwi
Pick dates
7:00 AM - 9:32 AM
United Airlines
1 Stops
4h 40m
TYS - SAT
$ 314
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Antonio (SAT)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.