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Cheap flights from Des Moines (DSM) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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Cheap flights from Des Moines to San Diego in April , May 2026

30 Apr - 20 May $ 396.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
DSM
Des Moines
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28 Apr - 09 May $ 867.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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27 Apr - 05 May $ 997.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Diego

27 Apr - 30 Apr $ 547.00
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
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27 Apr - 30 Apr $ 547.00
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
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27 Apr - 30 Apr $ 547.00
DSM
Des Moines
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
DSM
Des Moines
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One-way flights to San Diego from Des Moines

5:17 PM - 7:10 PM
United Airlines
1 Stops
5h 37m
DSM - SAN
$ 275
Kiwi
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1:32 PM - 6:40 PM
United Airlines
2 Stops
9h 1m
DSM - SAN
$ 370
Kiwi
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11:28 AM - 1:26 PM
United Airlines
1 Stops
5h 28m
DSM - SAN
$ 619
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.