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Cheap flights from Des Moines (DSM) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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Cheap flights from Des Moines to San Diego in November , December 2026

30 Nov - 03 Dec $ 238.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
DSM
Des Moines
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17 Nov - 10 Dec $ 788.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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19 Nov - 09 Dec $ 1,752.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Diego

23 Nov - 30 Nov $ 627.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
DSM
Des Moines
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27 Nov - 30 Nov $ 662.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
DSM
Des Moines
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15 Nov - 30 Nov $ 688.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
DSM
Des Moines
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One-way flights to San Diego from Des Moines

9:39 PM - 10:15 AM
Frontier Airlines
1 Stops
15h 58m
DSM - SAN
$ 145
Kiwi
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3:04 PM - 8:37 PM
Alaska Airlines
1 Stops
7h 56m
DSM - SAN
$ 489
Kiwi
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3:04 PM - 8:22 PM
Alaska Airlines
1 Stops
7h 41m
DSM - SAN
$ 582
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.