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Cheap flights from Des Moines (DSM) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
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Cheap flights from Des Moines to San Diego in February , March 2026

23 Feb - 06 Mar $ 199.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
11 Feb - 10 Mar $ 642.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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11 Feb - 04 Mar $ 647.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Diego

20 Feb - 01 Mar $ 301.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
23 Feb - 01 Mar $ 301.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Frontier Airlines
1 STOPS
DSM
Des Moines
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20 Feb - 01 Mar $ 321.00
DSM
Des Moines
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
2 STOPS
DSM
Des Moines
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One-way flights to San Diego from Des Moines

7:17 PM - 10:29 PM
Frontier Airlines
1 Stops
6h 51m
DSM - SAN
$ 137
Kiwi
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4:30 PM - 9:10 AM
Frontier Airlines
2 Stops
20h 24m
DSM - SAN
$ 298
Kiwi
Pick dates
4:30 PM - 7:30 AM
Frontier Airlines
2 Stops
18h 21m
DSM - SAN
$ 697
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.