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Cheap flights from Knoxville (TYS) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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Cheap flights from Knoxville to San Diego in November , December 2026

25 Nov - 13 Dec $ 416.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
TYS
Knoxville
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14 Nov - 06 Dec $ 733.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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14 Nov - 10 Dec $ 772.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to San Diego

25 Nov - 30 Nov $ 605.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
TYS
Knoxville
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14 Nov - 30 Nov $ 774.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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14 Nov - 30 Nov $ 938.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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One-way flights to San Diego from Knoxville

9:55 PM - 6:31 AM
Frontier Airlines
1 Stops
13h
TYS - SAN
$ 257
Kiwi
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11:51 AM - 3:34 PM
Alaska Airlines
1 Stops
7h 59m
TYS - SAN
$ 394
Kiwi
Pick dates
11:51 AM - 3:34 PM
Alaska Airlines
1 Stops
7h 59m
TYS - SAN
$ 553
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.