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Cheap flights from Knoxville (TYS) to San Diego (SAN)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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Cheap flights from Knoxville to San Diego in September , October 2026

30 Sep - 03 Oct $ 479.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
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15 Sep - 03 Oct $ 788.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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13 Sep - 03 Oct $ 899.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to San Diego

22 Sep - 30 Sep $ 514.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
14 Sep - 30 Sep $ 788.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
Pick dates
13 Sep - 30 Sep $ 899.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
Pick dates

One-way flights to San Diego from Knoxville

12:05 PM - 2:20 PM
United Airlines
1 Stops
6h 35m
TYS - SAN
$ 268
Kiwi
Pick dates
7:15 AM - 9:36 AM
United Airlines
1 Stops
6h 43m
TYS - SAN
$ 351
Kiwi
Pick dates
7:15 AM - 9:36 AM
United Airlines
1 Stops
6h 43m
TYS - SAN
$ 352
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.