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Cheap flights from Knoxville (TYS) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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Cheap flights from Knoxville to San Diego in November , December 2025

24 Nov - 11 Dec $ 308.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
TYS
Knoxville
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25 Nov - 09 Dec $ 737.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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25 Nov - 08 Dec $ 737.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to San Diego

24 Nov - 01 Dec $ 518.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
2 STOPS
TYS
Knoxville
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22 Nov - 01 Dec $ 888.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
2 STOPS
TYS
Knoxville
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22 Nov - 30 Nov $ 1,070.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
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One-way flights to San Diego from Knoxville

8:30 AM - 2:06 PM
Frontier Airlines
1 Stops
9h 57m
TYS - SAN
$ 203
Kiwi
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5:45 AM - 9:00 AM
United Airlines
1 Stops
8h 53m
TYS - SAN
$ 236
Kiwi
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4:58 PM - 7:24 PM
United Airlines
1 Stops
6h 56m
TYS - SAN
$ 384
Kiwi
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.