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Cheap flights from Knoxville (TYS) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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Cheap flights from Knoxville to San Diego in February , March 2026

28 Feb - 07 Mar $ 507.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
28 Feb - 07 Mar $ 507.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
Pick dates
28 Feb - 07 Mar $ 507.00
TYS
Knoxville
United Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
United Airlines
1 STOPS
TYS
Knoxville
Pick dates

One-way flights to San Diego from Knoxville

4:29 PM - 7:14 PM
Alaska Airlines
1 Stops
7h 8m
TYS - SAN
$ 266
Kiwi
Pick dates
7:05 AM - 9:30 AM
United Airlines
1 Stops
7h 9m
TYS - SAN
$ 266
Kiwi
Pick dates
5:40 AM - 8:38 AM
Alaska Airlines
1 Stops
7h 20m
TYS - SAN
$ 266
Kiwi
Pick dates

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.