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Cheap flights from Knoxville (TYS) to San Diego (SAN)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
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Cheap flights from Knoxville to San Diego in February , March 2026

27 Feb - 02 Mar $ 278.00
TYS
Knoxville
Frontier Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Frontier Airlines
1 STOPS
TYS
Knoxville
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27 Feb - 09 Mar $ 318.00
TYS
Knoxville
Frontier Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Frontier Airlines
1 STOPS
TYS
Knoxville
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27 Feb - 05 Mar $ 337.00
TYS
Knoxville
Allegiant Air
1 STOPS
SAN
San Diego
SAN
San Diego
Allegiant Air
1 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to San Diego

25 Feb - 28 Feb $ 510.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
Pick dates
25 Feb - 28 Feb $ 510.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
Pick dates
25 Feb - 28 Feb $ 510.00
TYS
Knoxville
Alaska Airlines
1 STOPS
SAN
San Diego
SAN
San Diego
Alaska Airlines
1 STOPS
TYS
Knoxville
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One-way flights to San Diego from Knoxville

6:51 PM - 10:29 PM
Frontier Airlines
1 Stops
8h 17m
TYS - SAN
$ 119
Kiwi
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6:59 AM - 9:30 AM
United Airlines
1 Stops
7h 6m
TYS - SAN
$ 264
Kiwi
Pick dates
6:59 AM - 9:30 AM
United Airlines
1 Stops
7h 6m
TYS - SAN
$ 364
Kiwi
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to San Diego (SAN)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.