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Cheap flights from Des Moines (DSM) to San Francisco (SFO)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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Cheap flights from Des Moines to San Francisco in November , December 2025

24 Nov - 05 Dec $ 350.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
19 Nov - 05 Dec $ 651.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier Airlines
1 STOPS
DSM
Des Moines
Pick dates
19 Nov - 08 Dec $ 651.00
DSM
Des Moines
Frontier Airlines
1 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier Airlines
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Francisco

24 Nov - 01 Dec $ 525.00
DSM
Des Moines
Allegiant Air
1 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
27 Nov - 01 Dec $ 744.00
DSM
Des Moines
United Airlines
1 STOPS
SFO
San Francisco
SFO
San Francisco
United Airlines
2 STOPS
DSM
Des Moines
Pick dates
19 Nov - 30 Nov $ 2,188.00
DSM
Des Moines
Alaska Airlines
1 STOPS
SFO
San Francisco
SFO
San Francisco
Alaska Airlines
1 STOPS
DSM
Des Moines
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One-way flights to San Francisco from Des Moines

6:05 AM - 9:51 AM
United Airlines
1 Stops
8h 5m
DSM - SFO
$ 225
Kiwi
Pick dates
9:01 AM - 1:25 PM
United Airlines
1 Stops
8h 15m
DSM - SFO
$ 265
Kiwi
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5:14 PM - 7:05 PM
United Airlines
1 Stops
5h 43m
DSM - SFO
$ 450
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.