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Cheap flights from Des Moines (DSM) to San Francisco (SFO)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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Cheap flights from Des Moines to San Francisco in September , October 2026

30 Sep - 29 Oct $ 509.00
DSM
Des Moines
Allegiant Air
1 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
30 Sep - 30 Oct $ 553.00
DSM
Des Moines
Allegiant Air
1 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
30 Sep - 22 Oct $ 553.00
DSM
Des Moines
Allegiant Air
1 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Francisco

29 Sep - 01 Oct $ 1,607.00
DSM
Des Moines
Allegiant Air
2 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
Pick dates
29 Sep - 01 Oct $ 1,676.00
DSM
Des Moines
Allegiant Air
2 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
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One-way flights to San Francisco from Des Moines

2:42 PM - 6:30 AM
Frontier Airlines
1 Stops
19h 32m
DSM - SFO
$ 382
Kiwi
Pick dates
11:33 AM - 1:29 PM
United Airlines
1 Stops
5h 42m
DSM - SFO
$ 581
Kiwi
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5:45 AM - 7:40 AM
United Airlines
1 Stops
5h 36m
DSM - SFO
$ 584
Kiwi
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.