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Cheap flights from Des Moines (DSM) to San Francisco (SFO)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
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Cheap flights from Des Moines to San Francisco in November , December 2026

23 Nov - 03 Dec $ 333.00
DSM
Des Moines
Allegiant Air
1 STOPS
SFO
San Francisco
SFO
San Francisco
Allegiant Air
1 STOPS
DSM
Des Moines
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19 Nov - 10 Dec $ 859.00
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
SFO
San Francisco
Alaska Airlines
2 STOPS
DSM
Des Moines
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19 Nov - 10 Dec $ 2,377.00
DSM
Des Moines
Alaska Airlines
2 STOPS
SFO
San Francisco
SFO
San Francisco
Alaska Airlines
2 STOPS
DSM
Des Moines
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Last minute flights from Des Moines to San Francisco

23 Nov - 30 Nov $ 887.00
DSM
Des Moines
WestJet
1 STOPS
SFO
San Francisco
SFO
San Francisco
WestJet
2 STOPS
DSM
Des Moines
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23 Nov - 01 Dec $ 889.00
DSM
Des Moines
WestJet
1 STOPS
SFO
San Francisco
SFO
San Francisco
WestJet
2 STOPS
DSM
Des Moines
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22 Nov - 30 Nov $ 919.00
DSM
Des Moines
WestJet
2 STOPS
SFO
San Francisco
SFO
San Francisco
WestJet
2 STOPS
DSM
Des Moines
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One-way flights to San Francisco from Des Moines

9:39 PM - 7:45 AM
Frontier Airlines
1 Stops
14h 1m
DSM - SFO
$ 211
Kiwi
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9:31 AM - 6:35 PM
Alaska Airlines
2 Stops
12h 45m
DSM - SFO
$ 539
Kiwi
Pick dates
9:45 AM - 6:35 PM
Alaska Airlines
2 Stops
12h 31m
DSM - SFO
$ 1,701
Kiwi
Pick dates

How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)

Related info for your journey
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How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Des Moines (DSM) to San Francisco (SFO)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.