Earn point on your loyalty program!arrow arc left

Cheap flights from Charleston (CHS) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)

How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Charleston to Santiago in August , September 2026

31 Aug - 23 Sep $ 716.00
CHS
Charleston
BREEZE
2 STOPS
SCL
Santiago
SCL
Santiago
BREEZE
2 STOPS
CHS
Charleston
Pick dates
31 Aug - 19 Sep $ 727.00
CHS
Charleston
BREEZE
2 STOPS
SCL
Santiago
SCL
Santiago
BREEZE
2 STOPS
CHS
Charleston
Pick dates
31 Aug - 25 Sep $ 809.00
CHS
Charleston
BREEZE
2 STOPS
SCL
Santiago
SCL
Santiago
BREEZE
2 STOPS
CHS
Charleston
Pick dates

Last minute flights from Charleston to Santiago

29 Aug - 02 Sep $ 1,017.00
CHS
Charleston
BREEZE
2 STOPS
SCL
Santiago
SCL
Santiago
BREEZE
2 STOPS
CHS
Charleston
Pick dates
24 Aug - 01 Sep $ 1,042.00
CHS
Charleston
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
3 STOPS
CHS
Charleston
Pick dates
29 Aug - 01 Sep $ 1,058.00
CHS
Charleston
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
3 STOPS
CHS
Charleston
Pick dates

One-way flights to Santiago from Charleston

9:44 PM - 12:01 PM
Copa Airlines
2 Stops
21h 48m
CHS - SCL
$ 360
Kiwi
Pick dates
7:00 AM - 3:08 PM
United Airlines
2 Stops
15h 43m
CHS - SCL
$ 731
Kiwi
Pick dates
11:10 AM - 9:39 PM
United Airlines
2 Stops
18h 4m
CHS - SCL
$ 731
Kiwi
Pick dates

How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charleston (CHS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.