Earn point on your loyalty program!arrow arc left

Cheap flights from Charlotte (CLT) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)

How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Charlotte to Santiago in December 2025 , January 2026

31 Dec - 26 Jan $ 642.00
CLT
Charlotte
Spirit Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
CLT
Charlotte
Pick dates
31 Dec - 24 Jan $ 642.00
CLT
Charlotte
Spirit Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
CLT
Charlotte
Pick dates
31 Dec - 29 Jan $ 654.00
CLT
Charlotte
Spirit Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
CLT
Charlotte
Pick dates

Last minute flights from Charlotte to Santiago

30 Dec - 01 Jan $ 936.00
CLT
Charlotte
Spirit Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
3 STOPS
CLT
Charlotte
Pick dates
23 Dec - 01 Jan $ 1,105.00
CLT
Charlotte
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
2 STOPS
CLT
Charlotte
Pick dates
23 Dec - 01 Jan $ 1,632.00
CLT
Charlotte
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
CLT
Charlotte
Pick dates

One-way flights to Santiago from Charlotte

2:57 PM - 7:20 PM
LATAM Airlines
1 Stops
12h 38m
CLT - SCL
$ 303
Kiwi
Pick dates
11:02 AM - 8:45 PM
United Airlines
2 Stops
19h 48m
CLT - SCL
$ 633
Kiwi
Pick dates
4:45 PM - 8:45 PM
United Airlines
1 Stops
14h 5m
CLT - SCL
$ 684
Kiwi
Pick dates

How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Charlotte (CLT) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.