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Cheap flights from Chicago (CHI) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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Cheap flights from Chicago to Santiago in December 2025 , January 2026

30 Dec - 23 Jan $ 687.00
CHI
Chicago
Avianca
1 STOPS
SCL
Santiago
SCL
Santiago
Avianca
1 STOPS
CHI
Chicago
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24 Dec - 08 Jan $ 1,010.00
CHI
Chicago
Avianca
1 STOPS
SCL
Santiago
SCL
Santiago
Avianca
1 STOPS
CHI
Chicago
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19 Dec - 10 Jan $ 4,054.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Santiago

22 Dec - 01 Jan $ 925.00
CHI
Chicago
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
CHI
Chicago
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29 Dec - 01 Jan $ 979.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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19 Dec - 01 Jan $ 2,977.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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One-way flights to Santiago from Chicago

7:10 AM - 7:12 PM
Arajet
1 Stops
17h 50m
CHI - SCL
$ 332
Kiwi
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10:20 PM - 7:15 AM
Avianca
1 Stops
14h
CHI - SCL
$ 393
Kiwi
Pick dates
10:20 PM - 7:15 AM
Avianca
1 Stops
14h
CHI - SCL
$ 393
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.