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Cheap flights from Chicago (CHI) to Santiago (SCL)

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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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Cheap flights from Chicago to Santiago in April , May 2026

27 Apr - 09 May $ 698.00
CHI
Chicago
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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12 Apr - 05 May $ 787.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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08 Apr - 09 May $ 790.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Santiago

27 Apr - 30 Apr $ 701.00
CHI
Chicago
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CHI
Chicago
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12 Apr - 01 May $ 1,019.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
CHI
Chicago
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08 Apr - 01 May $ 1,515.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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One-way flights to Santiago from Chicago

9:14 AM - 6:45 PM
Copa Airlines
2 Stops
16h 6m
CHI - SCL
$ 310
Kiwi
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11:20 PM - 7:15 AM
Avianca
1 Stops
13h 55m
CHI - SCL
$ 430
Kiwi
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5:59 PM - 10:10 PM
LATAM Airlines
1 Stops
12h 16m
CHI - SCL
$ 439
Kiwi
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.