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Cheap flights from Chicago (CHI) to Santiago (SCL)

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0 Children (2~11)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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Cheap flights from Chicago to Santiago in May , June 2026

28 May - 06 Jun $ 777.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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31 May - 06 Jun $ 799.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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28 May - 06 Jun $ 1,581.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Santiago

28 May - 01 Jun $ 799.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
Pick dates
28 May - 01 Jun $ 799.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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28 May - 01 Jun $ 1,783.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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One-way flights to Santiago from Chicago

6:06 PM - 10:05 PM
LATAM Airlines
1 Stops
12h 9m
CHI - SCL
$ 454
Kiwi
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9:49 AM - 10:05 PM
LATAM Airlines
1 Stops
20h 26m
CHI - SCL
$ 454
Kiwi
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3:21 PM - 9:35 PM
Copa Airlines
1 Stops
12h 49m
CHI - SCL
$ 559
Kiwi
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.