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Cheap flights from Chicago (CHI) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
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Cheap flights from Chicago to Santiago in August , September 2026

29 Aug - 25 Sep $ 565.00
CHI
Chicago
Copa Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
CHI
Chicago
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25 Aug - 04 Sep $ 765.00
CHI
Chicago
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
CHI
Chicago
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24 Aug - 02 Sep $ 1,212.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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Last minute flights from Chicago to Santiago

29 Aug - 31 Aug $ 710.00
CHI
Chicago
Copa Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
CHI
Chicago
Pick dates
24 Aug - 31 Aug $ 901.00
CHI
Chicago
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
CHI
Chicago
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24 Aug - 01 Sep $ 1,364.00
CHI
Chicago
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
CHI
Chicago
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One-way flights to Santiago from Chicago

3:21 PM - 10:55 AM
JetSMART
2 Stops
22h 5m
CHI - SCL
$ 263
Kiwi
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3:21 PM - 9:39 PM
Copa Airlines
1 Stops
12h 53m
CHI - SCL
$ 482
Kiwi
Pick dates
3:21 PM - 9:39 PM
Copa Airlines
1 Stops
12h 53m
CHI - SCL
$ 513
Kiwi
Pick dates

How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Chicago (CHI) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.