Earn point on your loyalty program!arrow arc left

Cheap flights from Cleveland (CLE) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)

How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Cleveland to Santiago in April , May 2026

20 Apr - 06 May $ 664.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates
27 Apr - 06 May $ 669.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates
26 Apr - 06 May $ 669.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates

Last minute flights from Cleveland to Santiago

20 Apr - 01 May $ 791.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates
27 Apr - 01 May $ 796.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates
26 Apr - 01 May $ 796.00
CLE
Cleveland
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
CLE
Cleveland
Pick dates

One-way flights to Santiago from Cleveland

8:50 AM - 6:45 PM
Copa Airlines
2 Stops
17h 30m
CLE - SCL
$ 316
Kiwi
Pick dates
6:00 AM - 3:08 PM
Copa Airlines
2 Stops
16h 43m
CLE - SCL
$ 588
Kiwi
Pick dates
4:26 PM - 7:50 PM
LATAM Airlines
1 Stops
13h 59m
CLE - SCL
$ 756
Kiwi
Pick dates

How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Cleveland (CLE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.