Earn point on your loyalty program!arrow arc left

Cheap flights from Denver (DEN) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Denver (DEN) to Santiago (SCL)

How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Denver to Santiago in March , April 2026

23 Mar - 22 Apr $ 640.00
DEN
Denver
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
1 STOPS
DEN
Denver
Pick dates
10 Mar - 10 Apr $ 988.00
DEN
Denver
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
DEN
Denver
Pick dates
03 Mar - 04 Apr $ 1,828.00
DEN
Denver
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
DEN
Denver
Pick dates

Last minute flights from Denver to Santiago

23 Mar - 01 Apr $ 697.00
DEN
Denver
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
1 STOPS
DEN
Denver
Pick dates
24 Mar - 01 Apr $ 703.00
DEN
Denver
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
1 STOPS
DEN
Denver
Pick dates
29 Mar - 01 Apr $ 703.00
DEN
Denver
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
1 STOPS
DEN
Denver
Pick dates

One-way flights to Santiago from Denver

11:49 PM - 4:30 PM
Sky Airline
2 Stops
19h 26m
DEN - SCL
$ 319
Kiwi
Pick dates
3:35 PM - 8:45 PM
United Airlines
1 Stops
13h 15m
DEN - SCL
$ 484
Kiwi
Pick dates
4:30 PM - 8:45 PM
United Airlines
1 Stops
12h 20m
DEN - SCL
$ 583
Kiwi
Pick dates

How to find the cheapest flight from Denver (DEN) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.