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Cheap flights from Denver (DEN) to Santiago (SCL)

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How to find the cheapest flight from Denver (DEN) to Santiago (SCL)

How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
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How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
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How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
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Cheap flights from Denver to Santiago in December 2025 , January 2026

31 Dec - 31 Jan $ 606.00
DEN
Denver
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
DEN
Denver
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21 Dec - 01 Jan $ 1,548.00
DEN
Denver
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
DEN
Denver
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21 Dec - 07 Jan $ 2,129.00
DEN
Denver
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
DEN
Denver
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Last minute flights from Denver to Santiago

24 Dec - 01 Jan $ 884.00
DEN
Denver
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
DEN
Denver
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24 Dec - 01 Jan $ 994.00
DEN
Denver
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
DEN
Denver
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18 Dec - 01 Jan $ 1,176.00
DEN
Denver
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
DEN
Denver
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One-way flights to Santiago from Denver

11:06 PM - 4:30 PM
Sky Airline
2 Stops
19h 9m
DEN - SCL
$ 263
Kiwi
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11:06 PM - 11:48 AM
Copa Airlines
2 Stops
17h 14m
DEN - SCL
$ 332
Kiwi
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3:41 PM - 8:45 PM
United Airlines
1 Stops
13h 9m
DEN - SCL
$ 553
Kiwi
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How to find the cheapest flight from Denver (DEN) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Denver (DEN) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.