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Cheap flights from Detroit (DTW) to Santiago (SCL)

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0 Children (2~11)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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Cheap flights from Detroit to Santiago in November , December 2025

25 Nov - 24 Dec $ 718.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
1 STOPS
DTW
Detroit
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30 Nov - 05 Dec $ 1,782.00
DTW
Detroit
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
DTW
Detroit
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30 Nov - 02 Dec $ 1,919.00
DTW
Detroit
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
DTW
Detroit
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Last minute flights from Detroit to Santiago

25 Nov - 01 Dec $ 1,089.00
DTW
Detroit
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
DTW
Detroit
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23 Nov - 01 Dec $ 1,276.00
DTW
Detroit
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
DTW
Detroit
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23 Nov - 01 Dec $ 1,762.00
DTW
Detroit
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
2 STOPS
DTW
Detroit
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One-way flights to Santiago from Detroit

7:00 AM - 9:35 PM
Avianca
2 Stops
20h 30m
DTW - SCL
$ 357
Kiwi
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4:47 PM - 8:45 PM
United Airlines
1 Stops
14h 3m
DTW - SCL
$ 710
Kiwi
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11:00 AM - 8:45 PM
United Airlines
2 Stops
19h 50m
DTW - SCL
$ 710
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.