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Cheap flights from Detroit (DTW) to Santiago (SCL)

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0 Children (2~11)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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Cheap flights from Detroit to Santiago in May , June 2026

28 May - 10 Jun $ 952.00
DTW
Detroit
Frontier Airlines
3 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
DTW
Detroit
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27 May - 06 Jun $ 1,510.00
DTW
Detroit
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
DTW
Detroit
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27 May - 05 Jun $ 1,531.00
DTW
Detroit
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
DTW
Detroit
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Last minute flights from Detroit to Santiago

28 May - 01 Jun $ 1,100.00
DTW
Detroit
Frontier Airlines
3 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
DTW
Detroit
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26 May - 01 Jun $ 1,109.00
DTW
Detroit
Frontier Airlines
3 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
DTW
Detroit
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27 May - 01 Jun $ 1,155.00
DTW
Detroit
Frontier Airlines
3 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
DTW
Detroit
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One-way flights to Santiago from Detroit

6:50 AM - 11:10 PM
LATAM Airlines
3 Stops
23h 10m
DTW - SCL
$ 527
Kiwi
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10:13 AM - 9:35 PM
Avianca
2 Stops
18h 32m
DTW - SCL
$ 707
Kiwi
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10:55 AM - 7:25 PM
United Airlines
2 Stops
16h 5m
DTW - SCL
$ 1,055
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.