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Cheap flights from Detroit (DTW) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
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Cheap flights from Detroit to Santiago in April , May 2026

14 Apr - 06 May $ 716.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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21 Apr - 06 May $ 722.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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14 Apr - 29 May $ 740.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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Last minute flights from Detroit to Santiago

14 Apr - 30 Apr $ 727.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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21 Apr - 30 Apr $ 733.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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27 Apr - 30 Apr $ 734.00
DTW
Detroit
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
DTW
Detroit
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One-way flights to Santiago from Detroit

5:20 AM - 6:39 PM
Arajet
2 Stops
21h 15m
DTW - SCL
$ 301
Kiwi
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7:04 PM - 3:08 PM
United Airlines
2 Stops
27h 39m
DTW - SCL
$ 691
Kiwi
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12:11 PM - 9:35 PM
United Airlines
2 Stops
16h 59m
DTW - SCL
$ 695
Kiwi
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Detroit (DTW) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.