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Cheap flights from Houston (HOU) to Santiago (SCL)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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Cheap flights from Houston to Santiago in March , April 2026

25 Mar - 14 Apr $ 582.00
HOU
Houston
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
HOU
Houston
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11 Mar - 02 Apr $ 860.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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11 Mar - 01 Apr $ 937.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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Last minute flights from Houston to Santiago

24 Mar - 31 Mar $ 694.00
HOU
Houston
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
1 STOPS
HOU
Houston
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11 Mar - 01 Apr $ 1,065.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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11 Mar - 31 Mar $ 1,316.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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One-way flights to Santiago from Houston

11:19 AM - 11:35 PM
JetSMART
2 Stops
15h 55m
HOU - SCL
$ 332
Kiwi
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5:35 PM - 7:15 AM
Avianca
2 Stops
19h 45m
HOU - SCL
$ 496
Kiwi
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8:45 PM - 8:45 PM
United Airlines
0 Stops
9h 5m
HOU - SCL
$ 1,535
Kiwi
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.