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Cheap flights from Houston (HOU) to Santiago (SCL)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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Cheap flights from Houston to Santiago in November , December 2025

28 Nov - 13 Dec $ 739.00
HOU
Houston
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
1 STOPS
HOU
Houston
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26 Nov - 09 Dec $ 1,252.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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26 Nov - 09 Dec $ 1,401.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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Last minute flights from Houston to Santiago

28 Nov - 01 Dec $ 1,084.00
HOU
Houston
VivaAerobus
2 STOPS
SCL
Santiago
SCL
Santiago
VivaAerobus
2 STOPS
HOU
Houston
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25 Nov - 01 Dec $ 1,794.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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25 Nov - 30 Nov $ 2,864.00
HOU
Houston
United Airlines
DIRECT
SCL
Santiago
SCL
Santiago
United Airlines
DIRECT
HOU
Houston
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One-way flights to Santiago from Houston

8:29 AM - 6:51 PM
Copa Airlines
2 Stops
15h 55m
HOU - SCL
$ 399
Kiwi
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4:35 PM - 9:35 PM
Avianca
2 Stops
33h 55m
HOU - SCL
$ 623
Kiwi
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8:45 PM - 8:45 PM
United Airlines
0 Stops
9h 5m
HOU - SCL
$ 1,311
Kiwi
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.