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Cheap flights from Houston (HOU) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
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Cheap flights from Houston to Santiago in April , May 2026

20 Apr - 23 May $ 678.00
HOU
Houston
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
HOU
Houston
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08 Apr - 05 May $ 888.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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11 Apr - 09 May $ 2,384.00
HOU
Houston
Avianca
1 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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Last minute flights from Houston to Santiago

20 Apr - 01 May $ 685.00
HOU
Houston
Spirit Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Spirit Airlines
2 STOPS
HOU
Houston
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08 Apr - 01 May $ 890.00
HOU
Houston
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
HOU
Houston
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16 Apr - 30 Apr $ 2,323.00
HOU
Houston
United Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
United Airlines
1 STOPS
HOU
Houston
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One-way flights to Santiago from Houston

11:39 AM - 1:00 AM
Sky Airline
2 Stops
16h 51m
HOU - SCL
$ 319
Kiwi
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5:45 PM - 4:20 PM
Avianca
2 Stops
28h 35m
HOU - SCL
$ 522
Kiwi
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5:45 PM - 7:15 AM
Avianca
2 Stops
19h 30m
HOU - SCL
$ 525
Kiwi
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Houston (HOU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.