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Cheap flights from Knoxville (TYS) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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Cheap flights from Knoxville to Santiago in March , April 2026

25 Mar - 18 Apr $ 706.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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23 Mar - 18 Apr $ 718.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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23 Mar - 18 Apr $ 743.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to Santiago

25 Mar - 01 Apr $ 802.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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23 Mar - 01 Apr $ 814.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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23 Mar - 01 Apr $ 839.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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One-way flights to Santiago from Knoxville

8:30 AM - 7:25 PM
Copa Airlines
2 Stops
18h 28m
TYS - SCL
$ 342
Kiwi
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2:06 PM - 9:32 PM
LATAM Airlines
2 Stops
16h 34m
TYS - SCL
$ 354
Kiwi
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2:06 PM - 9:28 PM
Copa Airlines
2 Stops
14h 54m
TYS - SCL
$ 379
Kiwi
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.