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Cheap flights from Knoxville (TYS) to Santiago (SCL)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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Cheap flights from Knoxville to Santiago in April , May 2026

27 Apr - 08 May $ 707.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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27 Apr - 29 May $ 716.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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20 Apr - 29 May $ 727.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to Santiago

27 Apr - 30 Apr $ 751.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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20 Apr - 30 Apr $ 755.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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20 Apr - 30 Apr $ 762.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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One-way flights to Santiago from Knoxville

1:15 PM - 9:35 PM
Copa Airlines
2 Stops
15h 55m
TYS - SCL
$ 326
Kiwi
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11:25 AM - 7:25 PM
United Airlines
2 Stops
15h 35m
TYS - SCL
$ 810
Kiwi
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9:00 AM - 9:35 PM
United Airlines
2 Stops
20h 10m
TYS - SCL
$ 810
Kiwi
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.