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Cheap flights from Knoxville (TYS) to Santiago (SCL)

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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
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Cheap flights from Knoxville to Santiago in November , December 2026

26 Nov - 11 Dec $ 749.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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17 Nov - 11 Dec $ 759.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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25 Nov - 11 Dec $ 787.00
TYS
Knoxville
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
2 STOPS
TYS
Knoxville
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Last minute flights from Knoxville to Santiago

26 Nov - 01 Dec $ 1,055.00
TYS
Knoxville
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
TYS
Knoxville
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17 Nov - 01 Dec $ 1,071.00
TYS
Knoxville
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
TYS
Knoxville
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25 Nov - 01 Dec $ 1,094.00
TYS
Knoxville
LATAM Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
2 STOPS
TYS
Knoxville
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One-way flights to Santiago from Knoxville

9:30 AM - 8:30 PM
LATAM Airlines
2 Stops
20h 10m
TYS - SCL
$ 387
Kiwi
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8:30 AM - 6:47 PM
Arajet
2 Stops
17h 5m
TYS - SCL
$ 391
Kiwi
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6:30 AM - 7:11 PM
Copa Airlines
2 Stops
19h 8m
TYS - SCL
$ 425
Kiwi
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Knoxville (TYS) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.