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Cheap flights from Mcallen (MFE) to Santiago (SCL)

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0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)

How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)
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How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)
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How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)
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Cheap flights from Mcallen to Santiago in December 2025 , January 2026

28 Dec - 29 Jan $ 1,201.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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28 Dec - 29 Jan $ 1,206.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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28 Dec - 29 Jan $ 1,209.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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Last minute flights from Mcallen to Santiago

28 Dec - 02 Jan $ 1,389.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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28 Dec - 02 Jan $ 1,559.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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28 Dec - 01 Jan $ 1,612.00
MFE
Mcallen
Allegiant Air
2 STOPS
SCL
Santiago
SCL
Santiago
Allegiant Air
3 STOPS
MFE
Mcallen
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One-way flights to Santiago from Mcallen

4:55 PM - 8:45 PM
United Airlines
1 Stops
12h 55m
MFE - SCL
$ 633
Kiwi
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4:55 PM - 8:45 PM
United Airlines
1 Stops
12h 55m
MFE - SCL
$ 680
Kiwi
Pick dates
2:05 PM - 8:45 PM
United Airlines
1 Stops
15h 45m
MFE - SCL
$ 680
Kiwi
Pick dates

How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Mcallen (MFE) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.