Earn point on your loyalty program!arrow arc left

Cheap flights from Minneapolis (MSP) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)

How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Minneapolis to Santiago in November , December 2025

25 Nov - 12 Dec $ 819.00
MSP
Minneapolis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
MSP
Minneapolis
Pick dates
25 Nov - 25 Dec $ 871.00
MSP
Minneapolis
Sun Country Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Sun Country Airlines
1 STOPS
MSP
Minneapolis
Pick dates
25 Nov - 25 Dec $ 906.00
MSP
Minneapolis
Sun Country Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Sun Country Airlines
1 STOPS
MSP
Minneapolis
Pick dates

Last minute flights from Minneapolis to Santiago

25 Nov - 01 Dec $ 1,208.00
MSP
Minneapolis
Sun Country Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Sun Country Airlines
3 STOPS
MSP
Minneapolis
Pick dates
25 Nov - 01 Dec $ 1,323.00
MSP
Minneapolis
Sun Country Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Sun Country Airlines
3 STOPS
MSP
Minneapolis
Pick dates
25 Nov - 01 Dec $ 1,358.00
MSP
Minneapolis
Sun Country Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Sun Country Airlines
3 STOPS
MSP
Minneapolis
Pick dates

One-way flights to Santiago from Minneapolis

8:12 AM - 8:35 PM
LATAM Airlines
2 Stops
20h 28m
MSP - SCL
$ 474
Kiwi
Pick dates
8:12 AM - 9:35 PM
Avianca
2 Stops
18h 18m
MSP - SCL
$ 509
Kiwi
Pick dates
11:55 AM - 8:45 PM
United Airlines
1 Stops
17h 55m
MSP - SCL
$ 689
Kiwi
Pick dates

How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Minneapolis (MSP) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.